Pennsylvania houses a robust chemical manufacturing sector, integral to various industries. Companies here produce specialty chemicals, coatings, and personal care products, addressing increasing demand for sustainable solutions. Innovations in materials science are propelling the industry forward, enhancing performance and efficacy while minimizing environmental impact. Demand for customized products is on the rise, with manufacturers focusing on adaptability and operational efficiency. Rising regulations also call for strong practices in safety and environmental compliance, urging organizations to refine processes. Enhanced R&D initiatives are reshaping product offerings and quality standards, positioning Pennsylvania as a pivotal area for chemical innovation.

This list features 21 notable chemical manufacturing firms located in Pennsylvania, showcasing operations varying in size from small teams to larger corporations. Founded between 1907 and 2023, these companies are strategically located in cities like Pittsburgh, Morrisville, and Exton. They specialize in diverse products ranging from custom chemical solutions to specialty materials for vital industries. By providing comprehensive services, these firms play a crucial role in sectors such as pharmaceuticals and water treatment, establishing strong market positions and reputations for quality.

Continue reading to discover the top chemical manufacturing companies in Pennsylvania.

Top 21 Chemical Manufacturing Companies in Pennsylvania

1. Gelest, Inc.

• Website: gelest.com
• Ownership type: Corporate
• Headquarters: Morrisville, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 99%
• Latest funding: May 2020
• Founded year: 1991
• Headcount: 51-200
• LinkedIn: gelest

Gelest, Inc., based in Morrisville, Pennsylvania, is a chemical manufacturer that has been operational since 1991. The company specializes in producing silanes, silicones, metal-organics, and acrylates, catering to a variety of industries including microelectronics, pharmaceuticals, and personal care. Gelest is known for its high-quality chemical products and custom solutions, which are tailored to meet the specific requirements of its business customers. The company emphasizes innovation and provides technical support, ensuring that clients can effectively utilize their products. Gelest's commitment to growth is evident in their recent announcement of a new production facility, which is set to enhance their manufacturing capabilities and support their expanding customer base. As a subsidiary of Mitsubishi Chemical Corporation, Gelest benefits from a strong corporate backing, further solidifying its position in the chemical manufacturing sector.

2. AGC Chemicals Americas Inc.

• Website: agcchem.com
• Ownership type: Private
• Headquarters: Exton, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1907
• Headcount: 51-200
• LinkedIn: agc-chemicals-americas-inc.

AGC Chemicals Americas Inc., based in Exton, Pennsylvania, is a private chemical manufacturer with a history dating back to 1907. The company specializes in the production of fluoropolymer-based products and specialty materials. Their product range includes fluoropolymer resins, chemical membranes, and fine chemicals, which cater primarily to business customers across various sectors. AGC Chemicals serves industries such as aerospace, construction, energy, electronics, and life sciences, providing materials that enhance the performance and durability of components in demanding applications. The company operates a Business and Technology Center in Exton, where it invests in research and development to create innovative solutions that meet the evolving needs of its customers. AGC Chemicals is committed to sustainability and actively works to reduce its environmental impact by developing processes that save energy and minimize pollution.

3. Pressure Chemical Co.

• Website: presschem.com
• Ownership type: Private
• Headquarters: Pittsburgh, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1964
• Headcount: 11-50
• LinkedIn: pressure-chemical-co.

Pressure Chemical Co., based in Pittsburgh, Pennsylvania, has been a key player in the specialty chemical manufacturing industry since its inception in 1964. The company specializes in the development, piloting, and custom manufacturing of specialty chemicals, serving sectors such as aerospace, cosmetics, and electronics. With a workforce of 37 employees, Pressure Chemical is nimble yet capable, offering tailored chemical solutions and process development services. Their facility is equipped to handle a variety of complex chemistries, including alkoxylation, high-pressure processes, and polymerization. Over the years, they have partnered with numerous Fortune 500 companies, showcasing their ability to scale up processes and deliver innovative solutions. Their commitment to quality and customer collaboration has allowed them to thrive in a competitive market, making them a noteworthy entity in the chemical manufacturing landscape.

4. GEO Specialty Chemicals, Inc.

• Website: geosc.com
• Ownership type: Corporate
• Headquarters: Ambler, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 62%, United Kingdom (UK) 38%
• Latest funding: September 2019
• Founded year: 1993
• Headcount: 501-1000
• LinkedIn: geo-specialty-chemicals

GEO Specialty Chemicals, Inc., founded in 1993 and based in Ambler, Pennsylvania, is a manufacturer of specialty chemicals. The company produces a wide range of products tailored for various applications, including coatings, resins, and consumer health products. Their offerings cater to multiple sectors, such as manufacturing, agriculture, and health, showcasing their ability to provide innovative solutions and technical support to enhance product performance. GEO Specialty Chemicals operates with a workforce of approximately 501 to 1000 employees, with a significant presence in both the United States and the United Kingdom. The company has not reported any recent funding, indicating a stable operational model that relies on its established market presence and product portfolio.

5. Zeolyst International

• Website: zeolyst.com
• Ownership type: Private
• Headquarters: Conshohocken, Pennsylvania, United States (USA)
• Employee distribution: Netherlands 72%, United States (USA) 23%, China 5%
• Founded year: 1988
• Headcount: 201-500
• LinkedIn: zeolyst-international

Zeolyst International, founded in 1988 and based in Conshohocken, Pennsylvania, is a private chemical manufacturer specializing in zeolites and catalysts. The company is dedicated to providing innovative solutions that support advanced recycling, renewable fuels, and emission control. Their product lineup includes a range of zeolites tailored for specific industrial applications, such as Opal Infinity™ zeolites for plastic recycling and Opal Pure™ zeolites for emission control. With a workforce of around 201-500 employees, Zeolyst operates primarily in the petrochemical and renewable energy sectors, demonstrating a strong commitment to sustainability and technological advancement. The company has a significant presence in the Netherlands, the United States, and China, reflecting its global reach and influence in the chemical manufacturing industry.

6. Reaxis Inc

• Website: reaxis.com
• Ownership type: Corporate
• Headquarters: Mcdonald, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 92%, Netherlands 8%
• Latest funding: February 2025
• Founded year: 1965
• Headcount: 51-200
• LinkedIn: reaxis-inc

Reaxis Inc, founded in 1965 and located in McDonald, Pennsylvania, is a specialty chemical manufacturer known for producing a variety of metal-based additives and catalysts. The company has carved out a niche in the chemical industry by offering solutions that cater to the needs of manufacturers across several sectors, including plastics, coatings, and personal care. With a workforce of approximately 38 employees, Reaxis emphasizes innovation and quality, adhering to both domestic and international environmental and safety standards. Their product offerings include catalysts for esterification and transesterification, as well as complexing agents and plating agents. Reaxis has established itself as a key player in the market, particularly as the only US-based manufacturer of a wide range of metal-based additives. Their commitment to sustainability is reflected in their ISO 9001 and ISO 14001 certifications, which highlight their focus on quality management and environmental responsibility.

7. Cardolite Corporation

• Website: cardolite.com
• Ownership type: Private
• Headquarters: Bristol, Pennsylvania, United States (USA)
• Employee distribution: India 58%, United States (USA) 29%, Belgium 4%, Other 9%
• Founded year: 1984
• Headcount: 51-200
• LinkedIn: cardolite

Cardolite Corporation, founded in 1984 and based in Bristol, Pennsylvania, is a specialty chemicals manufacturer that specializes in innovative products derived from cashew nutshell liquid (CNSL). With a workforce of approximately 93 employees, the company serves various industries, including automotive, construction, and industrial sectors. Cardolite's product portfolio includes high-performance solutions for coatings, adhesives, composites, and friction materials, emphasizing sustainability and performance. Their technologies, such as Ultra LITE CNSL Technology and phenalkamines, enable the production of eco-friendly products that meet the growing demand for low VOC and renewable materials. Cardolite's commitment to research and development has positioned it as a significant player in the specialty chemicals market, providing tailored solutions to meet specific customer needs.

8. Henwil Custom Chemicals

• Website: henwil.com
• Ownership type: Venture Capital
• Headquarters: Newell, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Seed, $15,000, February 2015
• Founded year: 2005
• Headcount: 11-50
• LinkedIn: henwil-corporation

Henwil Custom Chemicals, established in 2005 and located in Newell, Pennsylvania, is a specialty chemical manufacturer that focuses on providing custom solutions for water treatment. The company offers a range of services, including custom blending, toll manufacturing, bulk breaking and packaging, warehousing, private labeling, and transloading. Henwil serves various industries, such as municipal water treatment, oil and gas, food processing, and industrial applications. Their product line includes chemicals for water clarification, foam control, scale and deposit control, and odor control, among others. With a team of knowledgeable chemists boasting over 30 years of experience, Henwil is dedicated to delivering high-quality chemical products tailored to meet the specific needs of their clients. The company has received seed funding, which supports its growth and operational capabilities.

9. Resin Solutions, LLC.

• Website: resinsolutions.com
• Ownership type: Private Equity
• Headquarters: Exton, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 89%, Italy 11%
• Latest funding: April 2023
• Founded year: 2023
• Headcount: 51-200
• LinkedIn: resin-solutions-inc

Resin Solutions, LLC. is a chemical manufacturer based in Exton, Pennsylvania, specializing in low molecular weight functional additives tailored for the adhesives, rubber, and thermoplastics industries. Founded in 2023, the company has quickly positioned itself as a provider of high-performance materials, with products such as Poly bd® and Dymalink® that serve critical roles in various applications across construction, automotive, and electronics sectors. Their business model emphasizes collaboration with customers to meet evolving market needs, showcasing their commitment to innovation. With a workforce of approximately 62 employees and a presence in both the United States and Italy, Resin Solutions is poised to make a significant impact in the chemical manufacturing landscape.

10. CRC Industries

• Website: crcindustries.com
• Ownership type: Corporate
• Headquarters: Horsham, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 58%, Australia 7%, Belgium 5%, Other 30%
• Latest funding: August 2020
• Founded year: 1958
• Headcount: 201-500
• LinkedIn: crc-industries

CRC Industries, founded in 1958 and based in Horsham, Pennsylvania, is a chemical manufacturer that specializes in chemical specialty products aimed at maintenance and repair. The company offers a wide array of products, including cleaners, lubricants, and corrosion inhibitors, catering to both professional and consumer markets. Their clientele spans various sectors, notably automotive and construction, where effective solutions for equipment and vehicle maintenance are crucial. With a workforce of approximately 476 employees, CRC Industries has established a significant presence in the chemical manufacturing industry. The company is committed to sustainability and corporate social responsibility, as evidenced by their EcoVadis Silver Medal recognition for their efforts in these areas. Their global reach includes operations in countries such as Australia, Belgium, New Zealand, and the United Kingdom, further solidifying their role in the international chemical market.

11. BioSpectra, Inc.

• Website: biospectra.us
• Ownership type: Private
• Headquarters: Bangor, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 96%, Philippines 2%, Canada 2%
• Founded year: 1994
• Headcount: 201-500
• LinkedIn: biospectra-inc

BioSpectra, Inc., founded in 1994 and based in Bangor, Pennsylvania, is a private pharmaceutical manufacturer that specializes in cGMP fine chemicals and biological buffers. The company serves a global clientele of bio-pharmaceutical firms, providing essential ingredients that are crucial for drug manufacturing. BioSpectra operates multiple facilities across the United States, ensuring that they can meet the increasing demands of the pharmaceutical industry. Their product offerings include bulk GMP biological buffers, excipients, and new chemical entities, all produced under stringent quality and regulatory standards. The company has established itself as a reliable source of high-purity pharmaceutical ingredients, playing a significant role in the production of COVID-19 vaccines and treatments. With a workforce of approximately 135 employees, BioSpectra continues to expand its capabilities and facilities to support the growing needs of its customers.

12. Kroff, Inc.

• Website: kroff.com
• Ownership type: Private
• Headquarters: Pittsburgh, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1988
• Headcount: 51-200
• LinkedIn: kroff-inc-

Kroff, Inc., based in Pittsburgh, Pennsylvania, is a private company founded in 1988 that specializes in water treatment solutions. With a workforce of approximately 85 employees, Kroff focuses on delivering tailored chemical and engineering solutions to a variety of sectors, including agriculture, aerospace, energy manufacture, and more. The company prides itself on its ability to provide customized products and services that address specific water treatment challenges faced by its clients. Kroff has treated over 200 billion gallons of water and removed five billion pounds of contaminants, showcasing its significant impact on environmental health. Their laboratory services, staffed by doctoral-level scientists, enable them to develop innovative solutions that meet stringent EPA regulations. Kroff's commitment to sustainability is evident in their efforts to capture CO2 and reduce overall water treatment costs for their clients. They have also achieved ISO-9001 certification, reflecting their dedication to quality management in their operations.

13. Neville Chemical Company

• Website: nevchem.com
• Ownership type: Private
• Headquarters: Pittsburgh, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1925
• Headcount: 51-200
• LinkedIn: neville-chemical-co

Neville Chemical Company, based in Pittsburgh, Pennsylvania, has been a player in the chemical manufacturing industry since its inception in 1925. The company specializes in producing low molecular weight thermoplastic and liquid resins, which are essential components in various applications across multiple industries. Their product range includes DCPD thermal resins, C9 aromatic resins, C5 aliphatic resins, and epoxy modifiers, among others. Neville Chemical serves key markets such as adhesives and sealants, paints and coatings, tires and rubber, and ink. Their commitment to innovation is evident in their custom solutions, which cater to specific client needs. With nearly a century of experience, Neville Chemical continues to focus on enhancing product quality and customer satisfaction, solidifying its position in the chemical manufacturing sector.

14. Blendco Systems

• Website: blendco.com
• Ownership type: Corporate
• Headquarters: Bristol, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: March 2009
• Founded year: 1970
• Headcount: 11-50
• LinkedIn: blendcosystems

Blendco Systems, based in Bristol, Pennsylvania, is a chemical manufacturer that specializes in producing a wide array of cleaning and detailing products primarily for the automotive sector. Founded in 1970, the company has built a reputation for delivering high-quality solutions that cater to the needs of car wash facilities and detailing services. Their product line includes detergents, polishes, protectants, and specialty cleaning agents, all designed to enhance the efficiency and effectiveness of car cleaning processes. Blendco Systems operates under the umbrella of DuBois Chemicals, which further strengthens its capabilities in providing technical support and innovative solutions. The company has not reported any recent funding, indicating a stable operational model focused on serving its established market.

15. Colorcon

• Website: colorcon.com
• Ownership type: Private
• Headquarters: Harleysville, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 30%, United Kingdom (UK) 18%, India 17%, Other 36%
• Founded year: 1961
• Headcount: 1001-5000
• LinkedIn: colorcon

Colorcon, founded in 1961 and based in Harleysville, Pennsylvania, specializes in the design and development of specialty excipients and functional packaging tailored for the pharmaceutical and nutritional industries. With a workforce of over 1,150 employees, the company operates globally, serving clients in various regions including the United States, United Kingdom, India, Brazil, and France. Colorcon's product offerings include a wide range of film coatings, excipients, and formulation development assistance, all aimed at improving patient compliance and product stability. Their commitment to innovation is evident in their solutions that address challenges such as medication adherence and product authentication. Colorcon's technical service teams provide expertise throughout the product development process, from concept to commercialization, ensuring that their clients can efficiently bring effective formulations to market.

16. Polysciences, Inc.

• Website: polysciences.com
• Ownership type: Private
• Headquarters: Warrington, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1961
• Headcount: 51-200
• LinkedIn: polysciences-inc-

Polysciences, Inc. is a private chemical manufacturer based in Warrington, Pennsylvania, with a workforce of approximately 132 employees. Established in 1961, the company specializes in producing products for the life sciences and bioprocessing sectors. Their extensive catalog includes reagents, materials, and custom synthesis services tailored to meet the needs of laboratories and companies engaged in innovative research and therapeutic applications. Polysciences is particularly noted for its contributions to bioprocessing, histology, microscopy, and electronic chemicals. The company also offers contract manufacturing and custom synthesis services, which enhance their ability to support clients from initial concept through to commercialization. Their commitment to quality and innovation has made them a trusted partner in the chemical manufacturing industry.

17. Calgon Carbon Corporation

• Website: calgoncarbon.com
• Ownership type: Corporate
• Headquarters: Moon Township, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 92%, China 3%, Singapore 2%, Other 3%
• Latest funding: $1.1B, September 2017
• Founded year: 1942
• Headcount: 1001-5000
• LinkedIn: calgon-carbon-corporation

Calgon Carbon Corporation, founded in 1942 and based in Moon Township, Pennsylvania, is a manufacturer specializing in air and water purification solutions. The company produces a wide range of activated carbon products and offers reactivation services aimed at effective contaminant removal. Their products serve various markets, including industrial, municipal, and consumer applications, addressing critical needs in water treatment, air quality, and environmental remediation. Calgon Carbon operates in North America, Asia, and Europe, showcasing its global reach. The company has also been active in responding to emerging contaminants and regulatory challenges, such as the recent EPA regulations on PFAS levels, demonstrating its commitment to innovation and environmental stewardship. With a workforce of around 710 employees, Calgon Carbon continues to play a vital role in the chemical manufacturing industry, particularly in the field of environmental solutions.

18. Callery, LLC

• Website: callery.com
• Ownership type: Corporate
• Headquarters: Evans City, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: September 2019
• Founded year: 2017
• Headcount: 51-200
• LinkedIn: callery-llc

Callery, LLC, also known as Ascensus Specialties, is a specialty chemical manufacturer based in Evans City, Pennsylvania. Founded in 2017, the company specializes in providing high-quality reagents and custom synthesis services tailored to the needs of various industries, including pharmaceuticals and fine chemicals. Callery is dedicated to delivering reliable products and solutions, ensuring consistent quality and support throughout the development and production processes. Their product offerings include alkali metals, boranes, borohydrides, boronic acids and esters, and specialty alcoholates, which are essential in chemical synthesis and various applications. The company operates under strict quality management protocols, including cGMP standards, to maintain high levels of safety and efficacy in their products. With a workforce of 51-200 employees, Callery is positioned to support both small-scale and large-scale production needs, making it a valuable partner in the chemical manufacturing industry.

19. Chemstream

• Website: chemstream.com
• Ownership type: Private
• Headquarters: Homer, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1997
• Headcount: 201-500
• LinkedIn: chemstream-inc.

Chemstream, founded in 1997 and based in Homer, Pennsylvania, is a specialty chemical manufacturer and distributor. The company provides tailored chemical solutions to a variety of industries, including oil and gas, mining, and water treatment. Chemstream's product line features innovative offerings such as corrosion inhibitors, defoamers, and microbiological control agents, which are designed to help businesses effectively manage operational challenges. With a strong focus on customer service and environmental compliance, Chemstream operates a state-of-the-art laboratory that supports its commitment to delivering customized solutions. The company has built a reputation for its expertise in water treatment and environmental solutions, making it a relevant player in the chemical manufacturing industry.

20. Gannett Fleming Project Development Corporation

• Website: gfpdc.com
• Ownership type: Private
• Headquarters: Camp Hill, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1998
• Headcount: 11-50
• LinkedIn: gannett-fleming-project-development-corporation

Gannett Fleming Project Development Corporation, based in Camp Hill, Pennsylvania, was founded in 1998. The company specializes in the manufacturing of sodium sulfite and sodium bisulfite, essential chemicals utilized across various industries, including metallurgy, power generation, and water treatment. Their products play a crucial role in industrial processes, particularly in water treatment applications where they help in deoxygenating water to prevent corrosion in boilers. Gannett Fleming Project Development Corporation emphasizes quality and technological advancement in its production processes, aiming to meet the needs of its clients effectively. The company operates with a small team of around 16 employees, indicating a focused approach to its manufacturing capabilities.

21. Sylvin Technologies, Inc.

• Website: sylvin.com
• Ownership type: Venture Capital
• Headquarters: Denver, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: January 2018
• Founded year: 1978
• Headcount: 11-50
• LinkedIn: sylvin-technologies-inc

Sylvin Technologies, Inc., based in Denver, Pennsylvania, is a manufacturer that specializes in polymer compounds and additives. Founded in 1978, the company has carved out a niche in providing high-performance materials tailored for various applications across industries such as automotive and healthcare. Their product range includes a wide array of polymer formulations and food preservation additives, addressing the specific needs of businesses that require durable and functional products. Sylvin Technologies is part of the Alphagary group, which has expanded through innovation and acquisition, allowing them to serve global customers with locally responsive solutions. The company is committed to sustainable development and actively works on creating materials that meet the evolving demands of their clients. With a workforce of 29 employees, Sylvin Technologies continues to play a significant role in the chemical manufacturing sector, focusing on quality and performance in their offerings.

Chemical Manufacturing Insights: Key Companies in Pennsylvania

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