Xiidra, the proprietary name for prescription eye-drop Lifitegrast, is particularly respected in the healthcare industry for its effectiveness in addressing the symptoms of dry eye disease. Its impact has seen it dominate the global eye care industry, an arena bristling with competitors all aiming to innovate and improve patient care. Companies vary from pharmaceutical majors focusing on broad-ranging eye care solutions to specialized biotech firms targeting genetic factors or chronic conditions. As the search for superior alternatives continues, we see the prominence of organizations like EyePoint Pharmaceuticals and Sylentis pushing forward with their respective treatments that positions the industry on an upward trajectory of growth and breakthroughs.


Top 19 Xiidra alternatives

1. EyePoint Pharmaceuticals

  • Website: eyepointpharma.com
  • Headquarters: Watertown, Massachusetts, United States
  • Founded: 1987
  • Headcount: 51-200
  • Latest funding type: Post Ipo Debt
  • LinkedIn

EyePoint Pharmaceuticals, Inc. is a pharmaceutical company dedicated to developing and commercializing innovative therapeutics to improve the lives of patients with serious eye disorders. With a focus on transforming the treatment of wet AMD, diabetic retinopathy, and retinal vein occlusion, EyePoint offers a range of products including YUTIQ and DEXYCU. With their expertise in sustained-release drug delivery and localized treatments, they aim to provide long-lasting relief for debilitating eye diseases.


2. Sylentis

Sylentis is a biotechnology company that specializes in gene silencing technology. They develop therapies to reduce the concentration of malfunctioning or excessive proteins that cause certain diseases. Their services include the development of RNAi-based compounds for a wide range of targets and oligonucleotide-based drug development.


3. Nacuity Pharmaceuticals, Inc.

  • Website: nacuity.com
  • Headquarters: Fort Worth, Texas, United States
  • Founded: 2017
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

Nacuity Pharmaceuticals is a biotech company focused on developing innovative therapies to address oxidative stress-related eye diseases and chronic conditions.


4. Farmigea

Farmigea is a pharmaceutical company specializing in research, manufacture, and commercialization of ophthalmic products. They offer a complete range of services, from contract manufacturing to regulatory assistance, making them a comprehensive partner in ophthalmology.


5. Cloudbreak Pharma

Cloudbreak Therapeutics is a clinical-stage biotechnology company that specializes in the development of ocular drugs to improve eye health and mitigate ocular diseases.


6. AffaMed Therapeutics

  • Website: affamed.com
  • Headquarters: Shanghai, New York, China
  • Founded: 2019
  • Headcount: 51-200
  • Latest funding type: Series B
  • LinkedIn

AffaMed Therapeutics is a late clinical-stage biopharmaceutical company focused on developing and commercializing transformative pharmaceutical products that address critical unmet medical needs in ophthalmology, neurology, and psychiatric disorders.


7. Altacor

  • Website: altacor-pharma.com
  • Headquarters: Reading, Berkshire, United Kingdom
  • Founded: 2007
  • Headcount: 11-50
  • Latest funding type: Acquired
  • LinkedIn

Altacor is a specialist ophthalmology company offering ocular surface disease and ophthalmic surgery products to healthcare professionals and consumers.


8. Sifi

  • Website: sifigroup.com
  • Headquarters: Aci Sant’Antonio, Italy, Italy
  • Founded: 1935
  • Headcount: 201-500
  • Latest funding type: Private Equity
  • LinkedIn

SIFI Group is a manufacturing company specializing in ophthalmic products for the treatment of eye infections, inflammations, and disorders. They are committed to providing high-quality medications and have a strong focus on corporate social responsibility.


9. Nicox

  • Website: nicox.com
  • Headquarters: Valbonne, Provence-Alpes-Cote D&S;Azur, France
  • Founded: 1996
  • Headcount: 11-50
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Nicox is an international ophthalmic company developing innovative therapeutics to help maintain vision and improve ocular health. Their vision is to become a fully integrated ophthalmic pharmaceutical company with a direct presence in the U.S. and in the major European markets.


10. Aerie Pharmaceuticals

  • Website: aeriepharma.com
  • Headquarters: Durham, North Carolina, United States
  • Founded: 2005
  • Headcount: 501-1000
  • Latest funding type: Acquired
  • LinkedIn

Aerie Pharmaceuticals is a company that specializes in discovering, developing, and commercializing innovative therapies for patients with glaucoma, ocular surface diseases, and retinal diseases.


11. Oyster Point Pharma

  • Website: oysterpointrx.com
  • Headquarters: Princeton, New Jersey, United States
  • Founded: 2015
  • Headcount: 201-500
  • Latest funding type: Acquired
  • LinkedIn

Oyster Point Pharma is a biopharmaceutical company that focuses on the discovery, development, and commercialization of innovative therapies for ophthalmic diseases. They are committed to advancing breakthrough science to provide patients and eye care professionals with the therapies they need.


12. Visus Therapeutics, Inc.

  • Website: visustx.com
  • Headquarters: Seattle, Washington, United States
  • Founded: 2019
  • Headcount: 11-50
  • Latest funding type: Debt Financing
  • LinkedIn

Visus Therapeutics is a clinical-stage pharmaceutical company specializing in the development of cutting-edge ophthalmic therapies to improve patient lives.


13. BIOFTA - Biodue SpA

  • Website: biofta.com
  • Headquarters: Sambuca Val Di Pesa, Firenze, Italy
  • Headcount: 51-200
  • LinkedIn

Biofta is an Italian company specializing in developing and commercializing innovative products in the field of ophthalmology, including eye drops and supplements for various eye conditions.


14. MedEdicus

MedEdicus is a learning portal offering continuing education courses for healthcare professionals. They provide online CME/CE monographs, webcasts, and activities covering various medical topics. Courses are available in ophthalmology, neurotrophic keratitis, ulcerative colitis, age-related macular degeneration, and more.


15. Alfa Intes Industria Terapeutica Splendore

Alfaintes.it is a company that specializes in innovative solutions in the ophthalmological segment. They offer nutraceutical products and treatments for various eye conditions, including age-related macular degeneration, diabetic retinopathy, and non-infectious uveitis with macular edema.


16. Scope

Scope Eye Care offers a range of eye care products designed to manage a variety of ocular surface diseases, including dry eye disease, MGD, and blepharitis.


17. Novaliq GmbH

  • Website: novaliq.com
  • Headquarters: Heidelberg, Baden-Wurttemberg, United States
  • Founded: 2007
  • Headcount: 51-200
  • Latest funding type: Series Unknown
  • LinkedIn

Novaliq is a biopharmaceutical company specializing in the development and commercialization of ocular therapeutics using the innovative EyeSol® water-free technology. Their products target key drivers of eye diseases and have shown significant improvement in clinical trials. They aim to transform established treatments and provide novel solutions for various indications.


18. Eyenovia, Inc.

  • Website: eyenovia.com
  • Headquarters: New York, New York, United States
  • Founded: 2014
  • Headcount: 51-200
  • Latest funding type: Post Ipo Debt
  • LinkedIn

Eyenovia, Inc. is a ophthalmic technology company that develops the Optejet® delivery system for various therapeutic programs. They offer drug-device combinations for mydriasis, presbyopia, and pediatric progressive myopia. Eyenovia's innovative eye medication delivery technology aims to improve effectiveness, safety, and patient compliance. With the potential for Bluetooth capability, the Optejet® dispenser can track patient adherence. It also reduces systemic exposure and toxicity compared to traditional eyedroppers, resulting in a better tolerability and safety profile for topical treatments.


19. Mimetogen Pharmaceuticals Inc.

  • Website: mimetogen.com
  • Headquarters: Montreal, Quebec, Canada
  • Founded: 2004
  • Headcount: 11-50
  • Latest funding type: Series Unknown
  • LinkedIn

Mimetogen, a pharmaceutical company, focuses on developing therapies for diseases affecting ocular and neurological tissues.


Want to find more Xiidra alternatives?


If you want to find more companies like Xiidra that offer innovative therapeutic solutions to various eye disorders you can do so with Inven. This list was built with Inven and there are hundreds of companies like these globally.


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