California's Top 20 Biotechnology Corporate Encyclopedia
California's Top 20 Biotechnology Corporate Encyclopedia
The biotechnology sector in California exhibits a vibrant ecosystem buoyed by a confluence of academic innovation, robust start-up culture, and large corporations. The area's companies largely delve into novel biomolecular and cellular processes to develop technologies and products that help in improving life quality. They engage in mobile health, medical diagnostics, drug discovery, and biofuels. California’s biotech companies, such as Amgen and Gilead Sciences, invent radical therapeutic approaches, from using engineered T-cells to treat cancer to pioneering biologic medications. In the foreseeable future, advances in Genetics, Cellular and Molecular biology may herald more efficacious treatments for hitherto incurable diseases.
Top 20 biotechnology companies in California
1. Amgen
- Website: amgen.com
- Headquarters: Thousand Oaks, California, United States
- Founded: 1980
- Headcount: 10001+
- Latest funding type: Post Ipo Debt
Amgen is a biotech company that pioneers the use of living cells to develop and manufacture biologic medicines. They lead and guide the biotech industry, focusing on treating serious illnesses and diseases with limited treatment options.
2. Gilead Sciences
- Website: gilead.com
- Headquarters: Foster City, California, United States
- Founded: 1987
- Headcount: 10001+
- Latest funding type: Ipo
Gilead is a global biopharmaceutical company focused on improving human health. They are committed to developing innovative therapies to address unmet medical needs in the areas of HIV/AIDS, liver diseases, and more. With a mission to advance global health, Gilead strives to provide medication access and make a positive impact on communities worldwide.
3. Kite Pharma
- Website: kitepharma.com
- Headquarters: Santa Monica, California, United States
- Founded: 2009
- Headcount: 1001-5000
- Latest funding type: Acquired
Kite Pharma is a leading company in cancer immunotherapy, specializing in engineered T cell therapy. They aim to revolutionize cancer treatment by utilizing genetically modified immune cells to target tumors. Kite offers potentially lifesaving therapies for patients with hematologic cancers and solid tumors, including allogeneic therapies. With a focus on curative treatments, Kite is dedicated to bringing innovative solutions to those in need.
4. BioMarin Pharmaceutical Inc.
- Website: biomarin.com
- Headquarters: San Rafael, California, United States
- Founded: 1997
- Headcount: 1001-5000
- Latest funding type: Post Ipo Debt
BioMarin is a pharmaceutical company specializing in genetic therapies. They develop and provide transformative treatments for various genetic diseases, such as Morquio A Syndrome, PKU, and MPS. With a focus on gene therapy research, BioMarin aims to maximize the impact of genetic innovation and improve patients' lives.
5. Crown Bioscience
- Website: crownbio.com
- Headquarters: San Diego, California, United States
- Founded: 2006
- Headcount: 501-1000
- Latest funding type: Acquired
Crown Bioscience is a Contract Research Organization (CRO) that empowers customers to improve human health. They engage scientific talent, uphold quality standards, and pursue innovation to accelerate and de-risk drug development. Their services include biomarker discovery, efficacy testing, DMPK, and pharmacology.
6. Avid Bioservices
- Website: avidbio.com
- Headquarters: Tustin, California, United States
- Founded: 2002
- Headcount: 201-500
- Latest funding type: Post Ipo Debt
Avid Bioservices is a biotech company specializing in biologics drug development and manufacturing. They offer full lifecycle capabilities, from concept to commercial supply, and pride themselves on their personal commitment to project success. With state-of-the-art facilities in Orange County, California, they provide flexible options for mammalian cell culture production. Avid Bioservices also offers analytical services, quality and regulatory compliance, and viral vector development. They have a strong presence in the industry and actively participate in conferences and events.
7. Xencor
- Website: xencor.com
- Headquarters: Monrovia, California, United States
- Founded: 1997
- Headcount: 201-500
- Latest funding type: Post Ipo Equity
Xencor is a biotechnology company specializing in antibody and cytokine drug development. They utilize their XmAb® protein engineering platform to optimize drug candidates for the treatment of cancer and autoimmune disorders. With over 20 programs in clinical testing and a portfolio of marketed medicines, Xencor is at the forefront of developing innovative therapeutics.
8. Atum
- Website: atum.bio
- Headquarters: Newark, California, United States
- Founded: 2003
- Headcount: 51-200
ATUM.bio is a biotech company that offers a range of services and expertise in gene design, synthesis, protein engineering, antibody services, and cell line development. They collaborate with clients to achieve their research goals, providing solutions to optimize biological systems and advance their path to market.
9. Berkeley Lights
- Website: berkeleylights.com
- Headquarters: Emeryville, California, United States
- Founded: 2011
- Headcount: 201-500
- Latest funding type: Ipo
Berkeley Lights is a company that offers a fully integrated and end-to-end solution for cell-based breakthroughs. Their proprietary consumables, automation systems, and software enable researchers to efficiently discover high-value monoclonal antibodies and develop cell-based products. They aim to accelerate the use of cell-based products by providing researchers access to their platform, saving time and cost compared to traditional methods.
10. REVOLUTION Medicines
- Website: revmed.com
- Headquarters: Redwood City, California, United States
- Founded: 2014
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Revolution Medicines is a clinical-stage oncology company developing novel targeted therapies for RAS-addicted cancers.
11. Vineti
- Website: vineti.com
- Headquarters: San Francisco, California, United States
- Founded: 2016
- Headcount: 201-500
- Latest funding type: Series C
Vineti is a company that specializes in streamlining and optimizing the production process for cell therapies, gene therapies, and personalized cancer vaccines. They offer the PTM® Integration Suite, which connects critical systems and workflows together for improved operational efficiency and data collection. Vineti's solutions enable individualized therapies and support clinical trial programs in the healthcare industry.
12. Ambrx
- Website: ambrx.com
- Headquarters: San Diego, California, United States
- Founded: 2003
- Headcount: 51-200
- Latest funding type: Ipo
Ambrx is a biotechnology company that incorporates synthetic amino acids into proteins within living cells. They develop product candidates designed for highly stable, site-specific conjugation, overcoming the limitations of conventional conjugation approaches. Their focus is on advancing enhanced antibody drug conjugates and other engineered therapies to modulate the immune system for potential cancer treatments.
13. Ambys Medicines
- Website: ambys.com
- Headquarters: South San Francisco, California, United States
- Founded: 2018
- Headcount: 51-200
- Latest funding type: Series A
Ambys is a pharmaceutical company focused on developing cell therapies to treat severe liver diseases. They are driven by the urgent need to address this unaddressed healthcare problem. Their innovative approach aims to restore liver function and provide solutions for millions of patients globally.
14. Encoded Therapeutics Inc.
- Website: encoded.com
- Headquarters: South San Francisco, California, United States
- Founded: 2014
- Headcount: 51-200
- Latest funding type: Series D
Encoded Therapeutics is a company focused on translating next-generation science into transformative gene therapies. They aim to develop innovative treatments using gene therapy to address unmet medical needs.
15. Avidity Biosciences, Inc.
- Website: aviditybiosciences.com
- Headquarters: San Diego, California, United States
- Founded: 2013
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Avidity Biosciences is a company that is revolutionizing targeted RNA therapeutics. With their Antibody Oligonucleotide Conjugates (AOC) platform, they tackle the root cause of disease in muscle diseases and aim to expand into other therapeutic areas. Their innovative approach combines monoclonal antibodies and oligonucleotides to target previously inaccessible tissue and cell types.
16. Aadi Bioscience, Inc
- Website: aadibio.com
- Headquarters: Los Angeles, California, United States
- Founded: 2011
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Aadi Bioscience is a company focused on improving the lives of people with mTOR-driven diseases. They aim to address the limitations of current mTOR inhibitors and leverage genomic profiling technology to identify patients who will benefit from mTOR inhibition.
17. Atreca, Inc.
- Website: atreca.com
- Headquarters: South San Francisco, California, United States
- Founded: 2011
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Atreca is a biotech company specializing in the discovery and development of antibody-based cancer immunotherapeutics. They utilize a unique approach and advanced analysis of the immune response through their discovery platform.
18. Bolt Biotherapeutics, Inc.
- Website: boltbio.com
- Headquarters: Redwood City, California, United States
- Founded: 2015
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Bolt Biotherapeutics is a biotech company focused on developing immune-stimulating, myeloid-engaging therapeutics for the treatment of solid tumors, including HER2-low tumors. Leveraging their Boltbody™ ISAC approach and expertise in myeloid biology, they are dedicated to delivering transformative treatments for cancer patients with unmet medical needs.
19. Kindred Biosciences, Inc.
- Website: kindredbio.com
- Headquarters: Burlingame, California, United States
- Founded: 2012
- Headcount: 51-200
- Latest funding type: Acquired
KindredBio is a biotechnology company specializing in veterinary recombinant biologics manufacturing. They offer innovative products such as Mirataz™ (mirtazapine transdermal ointment) and are developing a pipeline including Zimeta™ (dipyrone) and epoCat™ (feline recombinant erythropoietin).
20. JOINN Biologics US Inc.
- Website: joinnbio.com
- Headquarters: Richmond, California, United States
- Founded: 2018
- Headcount: 51-200
- Latest funding type: Series B
JOINN Biologics is a full-service Contract Development and Manufacturing Organization (CDMO) located in Northern California. They offer a wide range of services including process development, formulation development, cell line development, analytical assay development, manufacturing, and quality control. With over two decades of experience, they provide support for the entire drug development process, from DNA to drug product. Their state-of-the-art facilities and expertise make them a trusted partner for pharmaceutical companies.
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