The biotechnology industry focuses on the use of living organisms and their products to develop new technologies and products that improve human health and the environment. Biotechnology companies in the US operate in various sectors, including pharmaceuticals, healthcare, agriculture, and industrial biotechnology. These companies leverage scientific advancements to develop and manufacture biologic medicines, innovative therapies, and molecular biology tools. They aim to address unmet medical needs, improve patient outcomes, and contribute to the overall well-being of society. The industry is continuously evolving, with advancements in genomics, gene editing, and personalized medicine. Biotechnology companies also play a crucial role in drug discovery, clinical trials, and collaboration with academic institutions and healthcare professionals. With the increasing demand for novel treatments and sustainable solutions, the biotechnology industry is poised for continued growth and innovation.


Top 20 Biotechnology Companies in the US

1. Amgen

  • Headquarter: Thousand Oaks, California, United States
  • Founded: 1980
  • Headcount: 10001+
  • Latest funding type: Post Ipo Debt
  • LinkedIn

Amgen is a biotech company that pioneers the use of living cells to develop and manufacture biologic medicines. They lead and guide the biotech industry, focusing on treating serious illnesses and diseases with limited treatment options.

2. Pfizer

  • Headquarter: New York, New York, United States
  • Headcount: 10001+
  • Latest funding type: Grant
  • LinkedIn

Pfizer Inc. is a leading biopharmaceutical company that specializes in the research, development, production, and distribution of innovative medicines and vaccines. With a commitment to improving global health, Pfizer strives to discover breakthrough treatments for various diseases, including cancer, infectious diseases, and inflammation. The company has a strong focus on patient care and collaboration with healthcare professionals to provide effective therapies. Pfizer's dedication to scientific innovation, ethical leadership, and sustainability makes it a trusted industry leader.

3. Regeneron

  • Headquarter: Tarrytown, New York, United States
  • Headcount: 5001-10000
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Regeneron Pharmaceuticals is a biopharmaceutical company that develops and manufactures biologic medicines. They are known for their commitment to scientific research and groundbreaking discoveries. Their goal is to improve human health through the development of innovative therapies.

4. Biogen

  • Headquarter: Cambridge, Massachusetts, United States
  • Headcount: 5001-10000
  • LinkedIn

Biogen is a science-driven company that aims to transform patient lives by solving societal problems. They focus on diseases like Amyotrophic Lateral Sclerosis, Alzheimer's Disease, and Multiple Sclerosis. Biogen offers a portfolio of medicines, including biosimilars, and is committed to diversity, equity, and inclusion. They have a strong R&D expertise and collaborate with partners for innovation. Biogen emphasizes access and health equity while prioritizing a healthy climate and global community.

5. GenScript

  • Headquarter: Piscataway, New Jersey, United States
  • Founded: 2002
  • Headcount: 5001-10000
  • LinkedIn

GenScript is a biotech company that specializes in molecular biology tools and services. They offer a wide range of products including peptides, antibodies, and protein expression tools. They also provide services such as gene synthesis, CRISPR genome editing, and antibody development.

6. BioMarin Pharmaceutical Inc.

  • Headquarter: San Rafael, California, United States
  • Founded: 1997
  • Headcount: 1001-5000
  • Latest funding type: Post Ipo Debt
  • LinkedIn

BioMarin is a pharmaceutical company specializing in genetic therapies. They develop and provide transformative treatments for various genetic diseases, such as Morquio A Syndrome, PKU, and MPS. With a focus on gene therapy research, BioMarin aims to maximize the impact of genetic innovation and improve patients' lives.

7. Zymergen, Inc.

  • Headquarter: Emeryville, California, United States
  • Founded: 2013
  • Headcount: 501-1000
  • Latest funding type: Series D
  • LinkedIn

Zymergen is a company that utilizes biology, chemistry, and technology to create innovative materials. By combining molecular biology, data science, automation, and genomics, they design molecules, microbes, and materials to meet the demands of their customers.

8. Twist Bioscience

  • Headquarter: South San Francisco, California, United States
  • Founded: 2013
  • Headcount: 501-1000
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Twist Bioscience is a company that focuses on driving biological innovations aimed at making the world safer, healthier, and more sustainable. They provide a wide range of products and services, including genes, oligo pools, NGS variant libraries, synthetic controls, antibody discovery, and SARS-CoV-2 tools.

9. Integrated DNA Technologies

  • Headquarter: Coralville, Iowa, United States
  • Founded: 1987
  • Headcount: 1001-5000
  • Latest funding type: Private Equity
  • LinkedIn

IDT (Integrated DNA Technologies) is a company that offers a wide range of products and services in the field of DNA and RNA research. They provide reagents, kits, and custom oligos for various applications such as gene expression analysis, genotyping, and NGS sequencing. IDT also offers solutions for CRISPR genome editing and RNA interference. With their comprehensive portfolio and expertise, IDT is committed to accelerating scientific research.

10. Crown Bioscience

  • Headquarter: San Diego, California, United States
  • Founded: 2006
  • Headcount: 501-1000
  • Latest funding type: Series D
  • LinkedIn

Crown Bioscience is a Contract Research Organization (CRO) that empowers customers to improve human health. They engage scientific talent, uphold quality standards, and pursue innovation to accelerate and de-risk drug development. Their services include biomarker discovery, efficacy testing, DMPK, and pharmacology.

11. CRISPR Therapeutics

  • Headquarter: Cambridge, Massachusetts, United States
  • Founded: 2013
  • Headcount: 201-500
  • Latest funding type: Grant
  • LinkedIn

CRISPR Therapeutics is a company that specializes in gene editing and cell therapies. They use the CRISPR/Cas9 therapeutic approach to treat genetically-defined diseases by editing cells inside the body.

12. Ginkgo Bioworks, Inc.

  • Headquarter: Boston, Massachusetts, United States
  • Founded: 2009
  • Headcount: 501-1000
  • Latest funding type: Series B
  • LinkedIn

Ginkgo Bioworks is a company that specializes in synthetic biology. They offer services such as enzyme discovery, engineering and optimization, strain improvement, and biosecurity program design. Their platform enables the design and production of various products including proteins, enzymes, small molecules, and biopharmaceuticals. They work with industries such as healthcare, agriculture, industrial chemicals, and food. Ginkgo Bioworks is revolutionizing industrial processes by harnessing the power of biology.

13. Amicus Therapeutics

  • Headquarter: Philadelphia, Pennsylvania, United States
  • Founded: 2002
  • Headcount: 501-1000
  • Latest funding type: Post Ipo Debt
  • LinkedIn

Amicus Therapeutics is a biotechnology company at the forefront of advanced therapies for rare genetic diseases. They develop innovative treatments and leverage technology platforms to improve the lives of patients. Their pipeline includes programs for Fabry Disease, Pompe Disease, Batten Disease, and other rare diseases. They offer products like Galafold® and Amicus Assist™.

14. United Therapeutics Corporation

  • Headquarter: Silver Spring, Maryland, United States
  • Founded: 1996
  • Headcount: 501-1000
  • LinkedIn

United Therapeutics is a company that focuses on the development and commercialization of innovative therapies for respiratory diseases and conditions. They offer a range of products and solutions aimed at improving the quality of life for patients suffering from pulmonary arterial hypertension and other related disorders.

15. Amyris

  • Headquarter: Emeryville, California, United States
  • Founded: 2003
  • Headcount: 1001-5000
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Amyris is a leading manufacturer of sustainable ingredients made with synthetic biology. Using sugarcane fermentation, they convert plant sugars into rare bioidentical molecules, essential ingredients, and clean, effective everyday products. They provide a scalable way forward in a world where demand for the earth's resources exceeds supply, making what is scarce abundant for all.

16. Synthego Corporation

  • Headquarter: Menlo Park, California, United States
  • Founded: 2012
  • Headcount: 201-500
  • Latest funding type: Series E
  • LinkedIn

Synthego is a company specializing in full stack genome engineering. They offer a range of products and services that enable researchers to design and modify DNA to advance scientific discovery and innovation.

17. Atum

  • Headquarter: Newark, California, United States
  • Founded: 2003
  • Headcount: 51-200
  • LinkedIn

ATUM.bio is a biotech company that offers a range of services and expertise in gene design, synthesis, protein engineering, antibody services, and cell line development. They collaborate with clients to achieve their research goals, providing solutions to optimize biological systems and advance their path to market.

18. Berkeley Lights

  • Headquarter: Emeryville, California, United States
  • Founded: 2011
  • Headcount: 201-500
  • Latest funding type: Series E
  • LinkedIn

Berkeley Lights is a company that offers a fully integrated and end-to-end solution for cell-based breakthroughs. Their proprietary consumables, automation systems, and software enable researchers to efficiently discover high-value monoclonal antibodies and develop cell-based products. They aim to accelerate the use of cell-based products by providing researchers access to their platform, saving time and cost compared to traditional methods.

19. Forge Biologics

  • Headquarter: Columbus, Ohio, United States
  • Founded: 2020
  • Headcount: 51-200
  • Latest funding type: Series C
  • LinkedIn

Forge Biologics is a company focused on developing innovative gene therapies to treat patients with devastating rare diseases. They offer end-to-end manufacturing services, from preclinical to commercial, to accelerate gene therapy programs. Their team of diverse and passionate individuals trailblazes a new model for making medicines. They specialize in AAV gene therapies and operate a state-of-the-art GMP facility called 'the Hearth.'

20. Chroma Medicine

  • Headquarter: Cambridge, Massachusetts, United States
  • Founded: 2021
  • Headcount: 51-200
  • LinkedIn

Chroma Medicine is a genomic medicine company that is developing a new class of therapeutics for precise control of gene expression. They aim to revolutionize treatment of diseases by harnessing epigenetics, nature's mechanism for gene regulation.

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