Top 21 Massachusetts Biopharmaceutical Innovators
Top 21 Massachusetts Biopharmaceutical Innovators
The biopharmaceutical industry in Massachusetts comprises of innovative businesses dedicated to developing and manufacturing medicines derived from biological sources. With a primary focus on conditions such as cancer, brain health disorders, and rare diseases, these companies strive to tackle the most pressing and intricate health challenges. Utilizing the latest technology, they engineer biological molecules and develop novel delivery systems. As the future of this industry unfolds, it is likely to be characterized by continual advancements, increased patient-centric approaches, greater collaboration, and efforts towards personalized medicine.
Top 21 biopharmaceutical companies in Massachusetts
1. Takeda Oncology
- Website: takedaoncology.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 1993
- Headcount: 1001-5000
Takeda Oncology is a pharmaceutical company dedicated to discovering and developing innovative therapies for the treatment of hematologic cancers and other blood diseases. They focus on breaking down barriers preventing the use of NGS and empowering patients through patient-centric partnerships. Their pipeline includes transformative treatments and they have a strong presence in the oncology field.
2. Sage Therapeutics
- Website: sagerx.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2010
- Headcount: 501-1000
- Latest funding type: Post Ipo Equity
Sage is a biopharmaceutical company committed to developing new medicines to treat life-altering brain health disorders.
3. Apellis Pharmaceuticals
- Website: apellis.com
- Headquarters: Waltham, Massachusetts, United States
- Founded: 2008
- Headcount: 201-500
- Latest funding type: Post Ipo Equity
Apellis Pharmaceuticals is a healthcare company that focuses on challenging conventional thinking in order to develop innovative treatments for patients with rare diseases. They specialize in ophthalmology and rare disease research, with a strong emphasis on complement science. The company is committed to championing patients and embracing the community voice in everything they do.
4. Blueprint Medicines
- Website: blueprintmedicines.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2011
- Headcount: 201-500
- Latest funding type: Post Ipo Equity
Blueprint Medicines is a precision therapeutics company that aims to develop therapies to improve the lives of patients. They combine protein kinase expertise with a focus on discovery and execution to create a deep pipeline of precision medicines.
5. Targanta Therapeutics
- Website: targanta.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2005
- Headcount: 51-200
- Latest funding type: Acquired
Targanta is a pharmaceutical company specializing in the discovery and development of antibacterial agents. They offer a drug discovery platform that focuses on targeting gram-positive pathogens, particularly Staphylococcus aureus. With a broad potential against these pathogens, Targanta aims to provide new solutions for the treatment of infectious diseases.
6. Arrakis Therapeutics
- Website: arrakistx.com
- Headquarters: Waltham, Massachusetts, United States
- Founded: 2015
- Headcount: 51-200
- Latest funding type: Series B
Arrakis is a company focused on pioneering RNA-targeted small molecule therapeutics. They are dedicated to the development and discovery of innovative medicines that can degrade RNA molecules. With a mission to explore and improve RNA-based treatments, Arrakis aims to make significant contributions in the field of molecular therapeutics.
7. X-Chem, Inc.
- Website: x-chemrx.com
- Headquarters: Waltham, Massachusetts, United States
- Founded: 2010
- Headcount: 51-200
- Latest funding type: Acquired
X-Chem is a leader in small molecule drug discovery and DNA-encoded library (DEL) technology. They combine DEL and medicinal chemistry expertise with groundbreaking AI solutions to accelerate the discovery of new drugs. Their services include DEL screening, custom synthesis, and medicinal chemistry. X-Chem's proprietary ArtemisAI technology revolutionizes the discovery of new medicines by utilizing machine learning models and extensive DEL data.
8. Laronde
- Website: laronde.bio
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2017
- Headcount: 11-50
- Latest funding type: Series B
Laronde is a company that specializes in the development and production of endless RNA (eRNA™), a new class of programmable medicines. With the potential to revolutionize the field of drug modality, eRNA offers therapeutic proteins that can be expressed inside the body by using non-coding regions to control expression, stability, targeting, and more.
9. FogPharma
- Website: fogpharma.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2016
- Headcount: 51-200
- Latest funding type: Series D
FogPharma is a fast-growing company specializing in the development of innovative precision medicines. Their first-in-class programs target elusive drivers of cancer, utilizing their Helicon polypeptides that combine the strength and specificity of antibodies with the benefits of small molecules. With a focus on achieving universal druggability, FogPharma is pioneering a new class of drugs to address the limitations of current precision medicines.
10. Spero Therapeutics
- Website: sperotherapeutics.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2013
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Spero Therapeutics is a global, multi-asset, clinical-stage biopharmaceutical company headquartered in Cambridge, Massachusetts. Their aim is to identify, develop, and commercialize novel treatments for multi-drug resistant bacterial infections and rare diseases.
11. Candel Therapeutics
- Website: candeltx.com
- Headquarters: Needham, Massachusetts, United States
- Founded: 1999
- Headcount: 51-200
- Latest funding type: Post Ipo Debt
Candeltx.com is a company that specializes in therapeutics and oncology research. They offer innovative treatments and solutions for various types of cancer. With a focus on research and development, the company aims to improve patient outcomes and revolutionize the field of oncology.
12. Xbiome
- Website: xbiome.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2017
- Headcount: 51-200
Xbiome.com is a leading pharmaceutical company specializing in AI technology for the analysis and optimization of gut microbiome. They offer innovative solutions for personalized medicine and drug development.
13. Tectonic Therapeutic, Inc.
- Website: tectonictx.com
- Headquarters: Watertown, Massachusetts, United States
- Founded: 2019
- Headcount: 11-50
- Latest funding type: Series A
Tectonic is a biotechnology company that focuses on the discovery and development of novel biologic therapeutics. Using molecular biology and Next Gen Sequencing analysis, Tectonic contributes to multiple drug discovery activities. The company strives to maintain processes and implement assays for the selection and assessment of clinical candidates.
14. Cullinan Oncology
- Website: cullinanoncology.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2017
- Headcount: 11-50
- Latest funding type: Post Ipo Equity
Cullinan Oncology is a company focused on targeted oncology research and development programs. They work towards innovating new therapies and treatments for patients with cancer.
15. Q-State Biosciences
- Website: qstatebio.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2013
- Headcount: 51-200
- Latest funding type: Grant
Q-State Biosciences is a company that combines biophysics and AI to build technology-derived medicines. They are focused on developing innovative treatments through their next generation Swarm™ optogenetic measurement technology system. The company has received multiple funding awards from the US National Institutes of Health and is dedicated to advancing healthcare through cutting-edge research.
16. Microfluidics International Corporation
- Website: microfluidics-mpt.com
- Headquarters: Westwood, Massachusetts, United States
- Founded: 1982
- Headcount: 51-200
Microfluidics is a company specializing in the development and manufacturing of high shear mixers and fluid processors for the biopharmaceutical industry. Their products enable efficient and precise liquid processing techniques, contributing to advancements in drug delivery, nanoparticle production, and biotechnology research.
17. Accent Therapeutics, Inc.
- Website: accenttx.com
- Headquarters: Lexington, Massachusetts, United States
- Founded: 2017
- Headcount: 11-50
- Latest funding type: Series B
Accent Therapeutics is a company focused on translating extraordinary science into life-changing therapies for patients in need. They apply proven drug discovery methods to a novel space in order to develop small molecule inhibitors of RNA-Modifying Proteins for the treatment of cancer.
18. Comanche Biopharma
- Website: comanchebiopharma.com
- Headquarters: Concord, Massachusetts, United States
- Founded: 2020
- Headcount: 11-50
Comanche Biopharma is a biotech company focused on developing innovative treatments for preeclampsia, a pregnancy complication affecting millions of women worldwide. Through groundbreaking gene silencing technology, they have created siRNA molecules that target and reduce the production of the protein responsible for preeclampsia. Their mission is to provide safe and effective solutions to this life-threatening condition, particularly for underserved populations.
19. Adiso Therapeutics
- Website: adisotx.com
- Headquarters: Concord, Massachusetts, United States
- Founded: 2022
- Headcount: 11-50
Adiso Therapeutics is a pharmaceutical company specializing in the development of therapies for inflammatory diseases. They aim to improve the lives of patients and their families by creating medicines that effectively treat these conditions. With a focus on reducing inflammation and addressing neutrophil-mediated tissue damage, Adiso Therapeutics is dedicated to providing innovative solutions for conditions such as ulcerative colitis and recurrent Clostridioides difficile infection.
20. Imara Inc.
- Website: imaratx.com
- Headquarters: Boston, Massachusetts, United States
- Founded: 2016
- Headcount: 11-50
- Latest funding type: Acquired
Imara, Inc. is a company dedicated to the development and commercialization of novel therapeutics for the treatment of serious diseases.
21. Neumora
- Website: neumoratx.com
- Headquarters: Watertown, Massachusetts, United States
- Founded: 2020
- Headcount: 51-200
- Latest funding type: Series B
Neumora is a neuroscience R&D company that utilizes precision data science to redefine the development of effective medicines for brain diseases. By integrating multiple types of data, their proprietary platform creates Data Biopsy Signatures™ and Precision Phenotypes™ to map disease drivers to patient subtypes, increasing the probability of successful therapeutics.
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