Top 22 US Biotechnology Firms Revealed
Top 22 US Biotechnology Firms Revealed
The biotechnology industry in the United States centers on developing innovative medicines, therapies, and techniques to foster human health. Comprising companies such as Pfizer, Amgen, and Gilead Sciences, the US biotech sector contributes to groundbreaking solutions for diseases and areas with unmet medical needs. These companies specialize in biopharmaceuticals, biologic medicines, and a clinical approach to tackling numerous health challenges such as cancer, infectious diseases, inflammation and more. The industry's trajectory appears promising as it constantly evolves and expands, with many companies committing to scientific discovery, sustainability, and global health advancement.
Top 22 biotechnology companies in the United States
1. Pfizer
- Website: pfizer.com
- Headquarters: New York, New York, United States
- Founded: 1849
- Headcount: 10001+
- Latest funding type: Grant
Pfizer Inc. is a leading biopharmaceutical company that specializes in the research, development, production, and distribution of innovative medicines and vaccines. With a commitment to improving global health, Pfizer strives to discover breakthrough treatments for various diseases, including cancer, infectious diseases, and inflammation. The company has a strong focus on patient care and collaboration with healthcare professionals to provide effective therapies. Pfizer's dedication to scientific innovation, ethical leadership, and sustainability makes it a trusted industry leader.
2. Amgen
- Website: amgen.com
- Headquarters: Thousand Oaks, California, United States
- Founded: 1980
- Headcount: 10001+
- Latest funding type: Post Ipo Debt
Amgen is a biotech company that pioneers the use of living cells to develop and manufacture biologic medicines. They lead and guide the biotech industry, focusing on treating serious illnesses and diseases with limited treatment options.
3. Gilead Sciences
- Website: gilead.com
- Headquarters: Foster City, California, United States
- Founded: 1987
- Headcount: 10001+
- Latest funding type: Ipo
Gilead is a global biopharmaceutical company focused on improving human health. They are committed to developing innovative therapies to address unmet medical needs in the areas of HIV/AIDS, liver diseases, and more. With a mission to advance global health, Gilead strives to provide medication access and make a positive impact on communities worldwide.
4. Regeneron
- Website: regeneron.com
- Headquarters: Tarrytown, New York, United States
- Founded: 1988
- Headcount: 5001-10000
- Latest funding type: Post Ipo Equity
Regeneron Pharmaceuticals is a biopharmaceutical company that develops and manufactures biologic medicines. They are known for their commitment to scientific research and groundbreaking discoveries. Their goal is to improve human health through the development of innovative therapies.
5. Biogen
- Website: biogen.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 1978
- Headcount: 5001-10000
Biogen is a science-driven company that aims to transform patient lives by solving societal problems. They focus on diseases like Amyotrophic Lateral Sclerosis, Alzheimer's Disease, and Multiple Sclerosis. Biogen offers a portfolio of medicines, including biosimilars, and is committed to diversity, equity, and inclusion. They have a strong R&D expertise and collaborate with partners for innovation. Biogen emphasizes access and health equity while prioritizing a healthy climate and global community.
6. Kite Pharma
- Website: kitepharma.com
- Headquarters: Santa Monica, California, United States
- Founded: 2009
- Headcount: 1001-5000
- Latest funding type: Acquired
Kite Pharma is a leading company in cancer immunotherapy, specializing in engineered T cell therapy. They aim to revolutionize cancer treatment by utilizing genetically modified immune cells to target tumors. Kite offers potentially lifesaving therapies for patients with hematologic cancers and solid tumors, including allogeneic therapies. With a focus on curative treatments, Kite is dedicated to bringing innovative solutions to those in need.
7. BioMarin Pharmaceutical Inc.
- Website: biomarin.com
- Headquarters: San Rafael, California, United States
- Founded: 1997
- Headcount: 1001-5000
- Latest funding type: Post Ipo Debt
BioMarin is a pharmaceutical company specializing in genetic therapies. They develop and provide transformative treatments for various genetic diseases, such as Morquio A Syndrome, PKU, and MPS. With a focus on gene therapy research, BioMarin aims to maximize the impact of genetic innovation and improve patients' lives.
8. Alnylam Pharmaceuticals
- Website: alnylam.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2002
- Headcount: 1001-5000
- Latest funding type: Post Ipo Debt
Alnylam is a biotechnology and pharmaceutical company that specializes in genetic medicines for central nervous system and ocular diseases. They are known for their innovative RNAi therapeutics that silence the genes causing human disease. They are committed to tackling complex health and societal challenges through their medicines and actions.
9. bluebird bio
- Website: bluebirdbio.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 1993
- Headcount: 1001-5000
- Latest funding type: Post Ipo Equity
Bluebird is a biotechnology company founded in 2010, specializing in ex-vivo gene therapy. With a focus on severe genetic diseases, they have industry-leading programs for sickle cell disease, β-thalassemia, and cerebral adrenoleukodystrophy.
10. Spark Therapeutics, Inc.
- Website: sparktx.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2013
- Headcount: 501-1000
- Latest funding type: Acquired
Spark is a gene therapy company that strives to challenge the inevitability of genetic disease. They aim to discover, develop, and deliver potential treatments in ways unimaginable, combining their proprietary gene therapy platform with excellence in research and manufacturing.
11. Crown Bioscience
- Website: crownbio.com
- Headquarters: San Diego, California, United States
- Founded: 2006
- Headcount: 501-1000
- Latest funding type: Acquired
Crown Bioscience is a Contract Research Organization (CRO) that empowers customers to improve human health. They engage scientific talent, uphold quality standards, and pursue innovation to accelerate and de-risk drug development. Their services include biomarker discovery, efficacy testing, DMPK, and pharmacology.
12. CRISPR Therapeutics
- Website: crisprtx.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2013
- Headcount: 201-500
- Latest funding type: Grant
CRISPR Therapeutics is a company that specializes in gene editing and cell therapies. They use the CRISPR/Cas9 therapeutic approach to treat genetically-defined diseases by editing cells inside the body.
13. Amicus Therapeutics
- Website: amicusrx.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2002
- Headcount: 501-1000
- Latest funding type: Post Ipo Debt
Amicus Therapeutics is a biotechnology company at the forefront of advanced therapies for rare genetic diseases. They develop innovative treatments and leverage technology platforms to improve the lives of patients. Their pipeline includes programs for Fabry Disease, Pompe Disease, Batten Disease, and other rare diseases. They offer products like Galafold® and Amicus Assist™.
14. United Therapeutics Corporation
- Website: unither.com
- Headquarters: Silver Spring, Maryland, United States
- Founded: 1996
- Headcount: 501-1000
- Latest funding type: Ipo
United Therapeutics is a company that focuses on the development and commercialization of innovative therapies for respiratory diseases and conditions. They offer a range of products and solutions aimed at improving the quality of life for patients suffering from pulmonary arterial hypertension and other related disorders.
15. Sirnaomics
- Website: sirnaomics.com
- Headquarters: Gaithersburg, Maryland, United States
- Founded: 2007
- Headcount: 51-200
- Latest funding type: Series E
Sirnaomics is a biotechnology company that specializes in RNAi therapeutics for the treatment of various diseases. They offer innovative solutions utilizing their GalNAc-based liver-targeting platforms and GalAhead™ programs. Sirnaomics is committed to developing cutting-edge therapies to improve patient outcomes.
16. Atum
- Website: atum.bio
- Headquarters: Newark, California, United States
- Founded: 2003
- Headcount: 51-200
ATUM.bio is a biotech company that offers a range of services and expertise in gene design, synthesis, protein engineering, antibody services, and cell line development. They collaborate with clients to achieve their research goals, providing solutions to optimize biological systems and advance their path to market.
17. Forge Biologics
- Website: forgebiologics.com
- Headquarters: Columbus, Ohio, United States
- Founded: 2020
- Headcount: 51-200
- Latest funding type: Series C
Forge Biologics is a company focused on developing innovative gene therapies to treat patients with devastating rare diseases. They offer end-to-end manufacturing services, from preclinical to commercial, to accelerate gene therapy programs. Their team of diverse and passionate individuals trailblazes a new model for making medicines. They specialize in AAV gene therapies and operate a state-of-the-art GMP facility called 'the Hearth.'
18. Ambrx
- Website: ambrx.com
- Headquarters: San Diego, California, United States
- Founded: 2003
- Headcount: 51-200
- Latest funding type: Ipo
Ambrx is a biotechnology company that incorporates synthetic amino acids into proteins within living cells. They develop product candidates designed for highly stable, site-specific conjugation, overcoming the limitations of conventional conjugation approaches. Their focus is on advancing enhanced antibody drug conjugates and other engineered therapies to modulate the immune system for potential cancer treatments.
19. Rocket Pharmaceuticals
- Website: rocketpharma.com
- Headquarters: Cranbury, New Jersey, United States
- Founded: 2015
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Rocket Pharmaceuticals is a biotech company that specializes in developing gene therapies for rare and complex inherited childhood disorders. Their mission is to provide curative treatments for patients with devastating diseases through first-in-class and best-in-class therapies. They prioritize patient support and community building throughout the treatment process.
20. BioPoint Inc.
- Website: biopointinc.com
- Headquarters: Peabody, Massachusetts, United States
- Founded: 2011
- Headcount: 51-200
Biopoint Inc. is a company that offers innovative solutions in the field of biotechnology. With a focus on research and development, they provide cutting-edge products and services to the biotech industry. Their offerings include advanced genetic engineering tools, laboratory equipment, and specialized biotech services.
21. Chroma Medicine
- Website: chromamedicine.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2021
- Headcount: 51-200
Chroma Medicine is a genomic medicine company that is developing a new class of therapeutics for precise control of gene expression. They aim to revolutionize treatment of diseases by harnessing epigenetics, nature's mechanism for gene regulation.
22. Remix Therapeutics
- Website: remixtx.com
- Headquarters: Cambridge, Massachusetts, United States
- Founded: 2018
- Headcount: 51-200
- Latest funding type: Series B
Remix Therapeutics is a company dedicated to addressing unmet medical needs by advancing their small molecule RNA reprogramming technology. They aim to generate novel therapeutics for patients and their caregivers.
Want to find more biotechnology companies?
If you want to find more companies that focus on innovating and producing advanced therapies you can do so with Inven. This list was built with Inven and there are hundreds of companies like these globally.
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- Ownership: Which of these are private equity backed? Which are family-owned?
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...and a lot more!
