23 Top-rated Biotechnology Firms in Pennsylvania
23 Top-rated Biotechnology Firms in Pennsylvania
The biotechnology industry in Pennsylvania presents a diverse array of companies aimed at revolutionizing health solutions. They champion advancements in areas like gene therapy, biomarker discovery, and formulation development. From manufacturing remedies for rare diseases to combatting genetic predispositions, these companies are ardent about saving lives and improving health standards. Leveraging unique platforms and proprietary technologies, they venture into research, clinical trials, and excellent manufacturing practices. As pioneers in the field, Pennsylvania’s biotech companies are set to foster heightened advancements in the industry in the coming years.
Top 23 biotechnology companies in Pennsylvania
1. CSL Behring
- Website: cslbehring.com
- Headquarters: King Of Prussia, Pennsylvania, United States
- Founded: 1904
- Headcount: 10001+
CSL Behring is a global biotech company that manufactures and sells products to treat rare diseases. They are driven by the promise to save lives and protect the health of people.
2. Spark Therapeutics, Inc.
- Website: sparktx.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2013
- Headcount: 501-1000
- Latest funding type: Acquired
Spark is a gene therapy company that strives to challenge the inevitability of genetic disease. They aim to discover, develop, and deliver potential treatments in ways unimaginable, combining their proprietary gene therapy platform with excellence in research and manufacturing.
3. Frontage Laboratories, Inc
- Website: frontagelab.com
- Headquarters: Exton, Pennsylvania, United States
- Founded: 2001
- Headcount: 501-1000
- Latest funding type: Ipo
Frontage Lab is a full service CRO that specializes in biomarker discovery and formulation development. They offer comprehensive laboratory testing, clinical trials management, and drug development services. With over 20 years of experience, they have completed more than 20 studies in Phase I-IIa. Frontage Lab provides services in clinical services, exome sequencing, genetic toxicology, mass spectrometry, and medicinal chemistry.
4. Amicus Therapeutics
- Website: amicusrx.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2002
- Headcount: 501-1000
- Latest funding type: Post Ipo Debt
Amicus Therapeutics is a biotechnology company at the forefront of advanced therapies for rare genetic diseases. They develop innovative treatments and leverage technology platforms to improve the lives of patients. Their pipeline includes programs for Fabry Disease, Pompe Disease, Batten Disease, and other rare diseases. They offer products like Galafold® and Amicus Assist™.
5. Abec
- Website: abec.com
- Headquarters: Bethlehem, Pennsylvania, United States
- Founded: 1974
- Headcount: 501-1000
- Latest funding type: Seed
ABEC is a bioprocess engineering and consulting company that provides customized solutions and services for biotech manufacturing. They offer process engineering, equipment, single-use solutions, and support for the development and manufacturing of biopharmaceutical products.
6. WuXi Advanced Therapies
- Website: advancedtherapies.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2004
- Headcount: 501-1000
Advanced Therapies is a cell and gene therapy development and manufacturing organization (CTDMO) based in Philadelphia, PA. They provide integrated contract testing, development, and manufacturing services for clinical and commercial cell and gene therapies. Their expertise includes viral clearance validation, analytical development, cell line characterization, and materials characterization.
7. Passage Bio
- Website: passagebio.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2017
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Passage Bio is a biotechnology company specializing in AAV gene therapies for CNS diseases. They focus on developing treatments for GM1 Gangliosidosis, Krabbe Disease, and Frontotemporal Dementia. Their commitment lies in providing patient and community resources to improve the lives of patients and their families. They also engage in collaboration and share their scientific advancements through partnerships with Penn GTP and innovative manufacturing practices.
8. Krystal Biotech, Inc.
- Website: krystalbio.com
- Headquarters: Pittsburgh, Pennsylvania, United States
- Founded: 2015
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Krystal Biotech is a biotechnology company focused on developing and commercializing genetic medicines for patients with rare diseases. They have a wide-ranging pipeline based on their proprietary redosable HSV vector. The company is headquartered in Pittsburgh, Pennsylvania, and has core capabilities in viral vector design, vector optimization, gene therapy manufacturing, and commercialization.
9. Venatorx Pharmaceuticals, Inc.
- Website: venatorx.com
- Headquarters: Malvern, Pennsylvania, United States
- Founded: 2010
- Headcount: 51-200
- Latest funding type: Series Unknown
Venatorx Pharmaceuticals is a private company focused on the discovery and development of novel anti-infectives to treat multi-drug-resistant (MDR) bacterial infections and hard-to-treat viral infections.
10. Marinus Pharma
- Website: marinuspharma.com
- Headquarters: Radnor, Pennsylvania, United States
- Founded: 2003
- Headcount: 51-200
- Latest funding type: Post Ipo Equity
Marinus Pharmaceuticals is a pharmaceutical company focused on developing therapies for seizure disorders. They aim to provide rapid cessation of status epilepticus and prevent treatment escalation. Their pipeline includes potential treatments for conditions such as tuberous sclerosis complex and CDKL5 deficiency disorder.
11. Aro Biotherapeutics
- Website: arobiotx.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2018
- Headcount: 11-50
- Latest funding type: Series B
Aro Biotherapeutics is a biotechnology company that specializes in the development of tissue-targeted genetic medicines using their proprietary protein technology called Centyrins. They are focused on creating a new class of receptor-targeted genetic medicines to modulate gene targets in disease tissues.
12. PhaseBio Pharmaceuticals, Inc.
- Website: phasebio.com
- Headquarters: Malvern, Pennsylvania, United States
- Founded: 2002
- Headcount: 11-50
- Latest funding type: Post Ipo Equity
PhaseBio Pharmaceuticals is a company dedicated to developing specialized and innovative therapies for cardiovascular diseases. With a focus on high-quality science, they aim to provide superior outcomes for patients and the healthcare system.
13. BriaCell Therapeutics Corp.
- Website: briacell.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2004
- Headcount: 11-50
- Latest funding type: Post Ipo Equity
BriaCell Therapeutics Corp. is a clinical-stage immunotherapy company focused on developing treatments for breast cancer. Their lead candidate, Bria-IMT™, is an immunotherapy approach that stimulates the body's own cancer-fighting cells to attack and destroy breast cancer tumors. They also have Bria-OTS™, an off-the-shelf personalized immunotherapy based on a patient's HLA-type. BriaCell is currently evaluating the safety and efficacy of Bria-IMT™ in combination with Incyte's immunotherapies. They have a strong management team and a clinical strategy team with experience in drug approvals.
14. Code Biotherapeutics
- Website: codebiotx.com
- Headquarters: Hatfield, Pennsylvania, United States
- Founded: 2020
- Headcount: 11-50
- Latest funding type: Series A
Code Biotherapeutics is a company actively engaged in establishing partnerships for the development of genetic medicines to treat rare and prevalent diseases. They are focused on leveraging their proprietary DNA delivery platform, 3DNA®, to overcome challenges in delivering genetic medicines and potentially cure life-threatening diseases.
15. Noveome Biotherapeutics, Inc.
- Website: noveome.com
- Headquarters: Pittsburgh, Pennsylvania, United States
- Founded: 2000
- Headcount: 11-50
- Latest funding type: Series Unknown
Noveome Biotherapeutics, Inc. is a biotech company specializing in the development of innovative biologics for a variety of medical conditions. They offer a portfolio of products targeting important ophthalmic indications. With a focus on scalable manufacturing, Noveome aims to provide cutting-edge treatments to patients in need.
16. Immunome, Inc.
- Website: immunome.com
- Headquarters: Exton, Pennsylvania, United States
- Founded: 2008
- Headcount: 11-50
- Latest funding type: Grant
Immunome is a biotech company specializing in the discovery and development of antibody-based therapeutics for areas of high unmet medical need, including cancer and infectious diseases.
17. ArriVent Biopharma
- Website: arrivent.com
- Headquarters: Pennsylvania Furnace, Pennsylvania, United States
- Founded: 2021
- Headcount: 11-50
- Latest funding type: Series B
ArriVent Biopharma is a pharmaceutical company that focuses on developing transformative medicines for cancer patients. They source scientifically validated discoveries globally and forge strategic collaborations to maximize therapeutic and market potential. Their goal is to provide patients worldwide with new treatment options.
18. Talee Bio
- Website: taleebio.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2016
- Headcount: 11-50
- Latest funding type: Grant
Spirovant Sciences is a bio-pharmaceutical company that specializes in developing gene therapy treatments for respiratory diseases.
19. Rosetta Genomics
- Website: rosettagenomics.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2000
- Headcount: 11-50
- Latest funding type: Acquired
Rosetta Genomics is a biotechnology company focused on developing and commercializing diagnostic tests and treatment solutions for cancer patients.
20. JacobsWyper Architects
- Website: jacobswyper.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 1981
- Headcount: 51-200
Jacobs Wyper Architects is a design firm that works with clients and partners to create innovative spaces where people can work more productively, make discoveries, and live healthier lives. They offer architecture and design services across various sectors including biotechnology, pharmaceuticals, community services, museums, education, industrial, and manufacturing.
21. Biosimilar Development
- Website: biosimilardevelopment.com
- Headquarters: Erie, Pennsylvania, United States
- Headcount: 51-200
Biosimilar Development provides content and resources for companies and professionals involved in the development, manufacturing, testing, and commercialization of biosimilars and biologics.
22. Jacobs Management Group, Inc.
- Website: jacobsmgt.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 1988
- Headcount: 11-50
Jacobs Management Group is a specialized recruitment firm that provides top industry talent for the medical device, pharmaceutical, biotech, and diagnostics industries. With over 30 years of experience, their expert search consultants connect clients with highly specialized positions ranging from executives to individual contributors.
23. LucasPye BIO
- Website: lucaspyebio.com
- Headquarters: Philadelphia, Pennsylvania, United States
- Founded: 2018
- Headcount: 11-50
- Latest funding type: Seed
LucasPye BIO is a biotech/biopharma company that manufactures biologics and offers expertise in accounts receivables/payables management, stainless steel/single-use equipment, and clinical compliance.
Want to find more biotechnology companies?
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