Biotechnology Standouts: Massachusetts' Top 24 Companies

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min read
Top 24 biotechnology companies in Massachusetts Main

Biotechnology Standouts: Massachusetts' Top 24 Companies

4
min read
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Top 24 biotechnology companies in Massachusetts Main
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The biotechnology industry in Massachusetts is a vibrant and innovative field, heavily oriented towards advanced research and development. Biotech companies here primarily focus on genetic medicine, pharmaceutical development, and gene-editing therapies, employing technology to address a host of complex diseases and disorders. These companies are spearheading radical solutions, often pioneering novel approaches in gene-editing and RNAi therapeutics. The market promises significant growth, shifting towards personalized medicine and custom therapeutic solutions. The sector also demonstrates significant potential for job creation and technology advancement.


Top 24 biotechnology companies in Massachusetts

1. Alnylam Pharmaceuticals

  • Website: alnylam.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2002
  • Headcount: 1001-5000
  • Latest funding type: Post Ipo Debt
  • LinkedIn

Alnylam is a biotechnology and pharmaceutical company that specializes in genetic medicines for central nervous system and ocular diseases. They are known for their innovative RNAi therapeutics that silence the genes causing human disease. They are committed to tackling complex health and societal challenges through their medicines and actions.


2. CRISPR Therapeutics

  • Website: crisprtx.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2013
  • Headcount: 201-500
  • Latest funding type: Grant
  • LinkedIn

CRISPR Therapeutics is a company that specializes in gene editing and cell therapies. They use the CRISPR/Cas9 therapeutic approach to treat genetically-defined diseases by editing cells inside the body.


3. Beam Therapeutics

  • Website: beamtx.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2017
  • Headcount: 501-1000
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Beam Therapeutics is a cutting-edge biotech company focused on base editing applications, delivering clinically validated technologies for gene-based editing. They offer a suite of innovative, nonviral and viral delivery modalities to advance the field of genetic medicine.


4. Intellia Therapeutics, Inc.

  • Website: intelliatx.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2014
  • Headcount: 201-500
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Intellia Therapeutics is a biotechnology company focused on developing CRISPR/Cas9 gene editing therapies. They are dedicated to transforming the lives of patients suffering from genetic diseases. Intellia Therapeutics is committed to using their expertise in genome editing to create innovative treatments.


5. Agios Pharmaceuticals

  • Website: agios.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2008
  • Headcount: 201-500
  • Latest funding type: Acquired
  • LinkedIn

Agios is a leading company in the field of cellular metabolism, focusing on advancing therapies for patients with genetically defined diseases. Their pioneering leadership and unique understanding of the science drives their success in developing groundbreaking therapies. They prioritize patient needs and collaboration with healthcare professionals and partners to ensure their therapies have the biggest impact possible.


6. Generate Biomedicines

Generate Biomedicines is a therapeutics company utilizing machine learning, biological engineering, and medicine to develop breakthrough medicines.


7. Editas Medicine

  • Website: editasmedicine.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2013
  • Headcount: 51-200
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Editas Medicine is a biotechnology company specializing in CRISPR gene editing. They offer innovative solutions for patients and focus on developing cutting-edge therapies. With a strong research pipeline and a dedicated team, Editas Medicine aims to revolutionize the field of genetic medicine.


8. Wave Life Sciences

  • Website: wavelifesciences.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2012
  • Headcount: 201-500
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Wave Life Sciences is a genetic medicines company that is focused on delivering life-changing treatments for people battling devastating diseases. They are creating a powerful genetic toolbox to develop potential medicines that reduce, restore, or modulate proteins responsible for genetic diseases.


9. Relay Therapeutics

  • Website: relaytx.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2016
  • Headcount: 51-200
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Relay Therapeutics is a drug discovery company that is revolutionizing the traditional approach by visualizing protein motion in HD movies. They are focused on bringing life-changing medicines to patients, with a pipeline of therapeutic candidates targeting precision oncology and genetic disease.


10. Genuity Science

  • Website: genuitysci.com
  • Headquarters: Boston, Massachusetts, United States
  • Founded: 2013
  • Headcount: 201-500
  • LinkedIn

Genuity Science is a company that specializes in biomarker discovery and offers biological data insights to accelerate precision medicine. They have expertise in massive, population-scale datasets and deep learning methods, enhanced by a data analysis platform built for population-scale genomics.


11. BioPoint Inc.

Biopoint Inc. is a company that offers innovative solutions in the field of biotechnology. With a focus on research and development, they provide cutting-edge products and services to the biotech industry. Their offerings include advanced genetic engineering tools, laboratory equipment, and specialized biotech services.


12. Chroma Medicine

Chroma Medicine is a genomic medicine company that is developing a new class of therapeutics for precise control of gene expression. They aim to revolutionize treatment of diseases by harnessing epigenetics, nature's mechanism for gene regulation.


13. Remix Therapeutics

  • Website: remixtx.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2018
  • Headcount: 51-200
  • Latest funding type: Series B
  • LinkedIn

Remix Therapeutics is a company dedicated to addressing unmet medical needs by advancing their small molecule RNA reprogramming technology. They aim to generate novel therapeutics for patients and their caregivers.


14. Senda Biosciences

  • Website: sendabiosciences.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2017
  • Headcount: 51-200
  • Latest funding type: Series C
  • LinkedIn

Senda Biosciences is a company dedicated to bringing life-changing treatments to patients by utilizing nature's codes to fully program medicines. Their mission is to unlock new levels of speed, breadth, and productivity in the development of advanced therapies.


15. Affinia Therapeutics

  • Website: affiniatx.com
  • Headquarters: Waltham, Massachusetts, United States
  • Founded: 2019
  • Headcount: 51-200
  • Latest funding type: Series B
  • LinkedIn

Affinia Therapeutics is a company specializing in gene therapy solutions. They aim to make a positive impact on individuals affected by rare and prevalent diseases. Through their proprietary ART platform, they use rational design science to develop transformative gene therapies. Affinia is at the forefront of adeno-associated virus (AAV) gene therapy, expanding the possibilities in treating devastating diseases.


16. Rhythm Pharmaceuticals Inc.

  • Website: rhythmtx.com
  • Headquarters: Boston, Massachusetts, United States
  • Founded: 2008
  • Headcount: 51-200
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Rhythm Pharmaceuticals is a company dedicated to transforming the care of people living with rare genetic diseases of obesity. They focus on the melanocortin-4 receptor (MC4R) pathway, which regulates weight and hunger.


17. Alloy Therapeutics, Inc.

  • Website: alloytx.com
  • Headquarters: Boston, Massachusetts, United States
  • Founded: 2017
  • Headcount: 51-200
  • Latest funding type: Series D
  • LinkedIn

Alloy Therapeutics is a biotechnology company based in Athens, GA. We empower drug discovery across 6 biologic modalities through our platforms, services, and company creation. We offer a spectrum of biologic discovery platforms to help research groups find the best drug against their target and develop innovative therapeutic formats.


18. Dyno Therapeutics

  • Website: dynotx.com
  • Headquarters: Watertown, Massachusetts, United States
  • Founded: 2018
  • Headcount: 51-200
  • Latest funding type: Series A
  • LinkedIn

Dyno Therapeutics is a cutting-edge company focused on next-gen gene therapy vectors for muscle disease. They are recognized as one of the most promising startups of 2021, with significant partnerships and awards. Their innovative lab and talented team drive their search for transformative vectors. With a recent successful Series A financing led by Andreessen Horowitz, Dyno is poised for further growth and success.


19. Foghorn Therapeutics Inc.

  • Website: foghorntx.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2016
  • Headcount: 51-200
  • Latest funding type: Ipo
  • LinkedIn

Foghorn Therapeutics is a pioneering biotech company that leverages unique insights into the chromatin regulatory system to develop a new class of precision therapeutic candidates. Their therapies correct abnormal gene expression, targeting disease dependencies and offering potential breakthroughs in treating cancer and other serious diseases.


20. Conagen

  • Website: conagen.com
  • Headquarters: Bedford, Massachusetts, United States
  • Founded: 2010
  • Headcount: 51-200
  • LinkedIn

Conagen is a company offering innovative solutions in the field of synthetic biology. They specialize in using cutting-edge biotechnology to develop sustainable and bio-based products for various industries.


21. Tome Biosciences

  • Website: tome.bio
  • Headquarters: Watertown, Massachusetts, United States
  • Founded: 2021
  • Headcount: 11-50
  • LinkedIn

Tome Biosciences is a company that specializes in programmable gene insertion. They offer innovative solutions in the field of bioengineering.


22. Xbiome

  • Website: xbiome.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2017
  • Headcount: 51-200
  • LinkedIn

Xbiome.com is a leading pharmaceutical company specializing in AI technology for the analysis and optimization of gut microbiome. They offer innovative solutions for personalized medicine and drug development.


23. ROME Therapeutics

  • Website: rometx.com
  • Headquarters: Boston, Massachusetts, United States
  • Founded: 2020
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

ROME Therapeutics is a pioneering company at the forefront of biology, focused on unlocking the potential of RNA for revolutionary therapeutics. With cutting-edge research and breakthrough technologies, we aim to harness the power of RNA to target and treat previously undruggable diseases.


24. hC Bioscience, Inc.

  • Website: hcbioscience.com
  • Headquarters: Cambridge, Massachusetts, United States
  • Founded: 2021
  • Headcount: 11-50
  • Latest funding type: Series A
  • LinkedIn

hC Bioscience is a pioneer in the development of tRNA-based therapeutics, focusing on creating engineered tRNAs to overcome disease-causing issues in the genetic code. With a team of experienced professionals and strategic partnerships, they aim to transform the treatment of genetic diseases and cancer.


Want to find more biotechnology companies?


If you want to find more companies that offer innovative gene-editing therapies and breakthrough RNAi therapeutics you can do so with Inven. This list was built with Inven and there are hundreds of companies like these globally.


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  • Ownership: Which of these are private equity backed? Which are family-owned?
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...and a lot more!

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