The cancer gene therapy industry encompasses a spectrum of biotechnology and pharmaceutical enterprises specializing in revolutionary treatments. These companies are geared towards developing modern, cancer-centric genetic therapies, focusing on areas like cell therapy, oncology research, and regenerative medicine. They propel clinical trials, advance drug development, and harness the human immune system for innovative cancer treatments. Equipped with the potential to redefine the cancer treatment framework, industry enablers, such as Novartis Nederland and Takara Bio Inc., are making headway. Operating amidst technological advancements and medical discoveries, the industry is heading towards a future where genetic alterations could play a pivotal role in cancer management.


Top 25 Cancer Gene Therapy Companies

1. Novartis Nederland

  • Website: novartis.nl
  • Headquarters: Amsterdam, North Holland, Netherlands
  • Founded: 1996
  • Headcount: 10001+
  • LinkedIn

Novartis is a pharmaceutical company that focuses on developing and producing medications. With a mission to improve people's health and well-being, Novartis offers a range of medicines for various therapeutic areas. They are committed to clinical research and innovation, particularly in the fields of cell and gene therapy.


2. Takara Bio Inc.

  • Website: takara-bio.com
  • Headquarters: Kusatsu, Gumma, Japan
  • Founded: 1925
  • Headcount: 1001-5000
  • Latest funding type: Ipo
  • LinkedIn

Takara Bio is a biotechnology company specializing in gene therapy and oncology research. They offer innovative solutions, including oncology drug development, clinical trials, and gene therapy products. With a focus on groundbreaking treatments, Takara Bio is committed to advancing the field of regenerative medicine.


3. Iovance Biotherapeutics, Inc.

  • Website: iovance.com
  • Headquarters: San Carlos, California, United States
  • Founded: 2007
  • Headcount: 201-500
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Iovance Biotherapeutics aims to be the global leader in developing and delivering tumor infiltrating lymphocyte (TIL) therapies for cancer patients. They harness the immune system's ability to recognize and destroy cancer cells in each patient, with their lead product candidate, lifileucel, showing promise for metastatic melanoma. They are committed to continuous innovation in cell therapy, including gene-edited therapies.


4. Vineti

  • Website: vineti.com
  • Headquarters: San Francisco, California, United States
  • Founded: 2016
  • Headcount: 201-500
  • Latest funding type: Series C
  • LinkedIn

Vineti is a company that specializes in streamlining and optimizing the production process for cell therapies, gene therapies, and personalized cancer vaccines. They offer the PTM® Integration Suite, which connects critical systems and workflows together for improved operational efficiency and data collection. Vineti's solutions enable individualized therapies and support clinical trial programs in the healthcare industry.


5. T-knife Therapeutics

  • Website: t-knife.com
  • Headquarters: San Francisco, Berlin, Costa Rica
  • Founded: 2018
  • Headcount: 51-200
  • Latest funding type: Series B
  • LinkedIn

T-knife is a biotech company focused on developing T cell receptor engineered T cell therapies (TCR-Ts) for patients with solid tumors. They leverage their proprietary MyT platform for TCR and epitope discovery to generate transformational responses. T-knife's approach targets tumor-specific antigens to stimulate a potent T cell-driven immune response.


6. SillaJen

  • Website: sillajen.com
  • Headquarters: San Francisco, California, United States
  • Founded: 2003
  • Headcount: 51-200
  • Latest funding type: Ipo
  • LinkedIn

Sillajen is a global leader in oncolytic immunotherapeutics, offering innovative solutions for targeting, attacking, and eradicating cancers. They specialize in developing advanced products like Pexa-Vec, which selectively infects and replicates in cancer cells by exploiting genetic changes. Sillajen is actively seeking development partners and licensing opportunities for all its assets.


7. KSQ Therapeutics, Inc.

  • Website: ksqtx.com
  • Headquarters: Lexington, Massachusetts, United States
  • Founded: 2015
  • Headcount: 11-50
  • Latest funding type: Series C
  • LinkedIn

KSQ Therapeutics is a biotechnology company specializing in CRISPRomics for immuno-oncology therapies. They have developed autologous cell therapy candidates, KSQ-001 and KSQ-004, which have shown transformational efficacy in preclinical models. Their proprietary CRISPRomics platform enables the identification of genomic targets for optimal potency, memory formation, and durability. KSQ-4279, a small molecule inhibitor, is also being developed as a pipeline of treatments for advanced solid tumors. With their innovative approach, KSQ Therapeutics aims to revolutionize the treatment of solid tumors.


8. Aro Biotherapeutics

  • Website: arobiotx.com
  • Headquarters: Philadelphia, Pennsylvania, United States
  • Founded: 2018
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

Aro Biotherapeutics is a biotechnology company that specializes in the development of tissue-targeted genetic medicines using their proprietary protein technology called Centyrins. They are focused on creating a new class of receptor-targeted genetic medicines to modulate gene targets in disease tissues.


9. GeneMedicine

  • Website: gene-medicine.com
  • Headquarters: Seoul, Seoul-T&S;Ukpyolsi, Korea (the Republic of)
  • Founded: 2014
  • Headcount: 11-50
  • Latest funding type: Series A
  • LinkedIn

GeneMedicine is a company specializing in the development of next-generation anti-cancer viruses. By leveraging their advanced platform technology, they aim to provide a healthy life to patients suffering from incurable cancer. They conduct research and development in the field of anti-cancer viruses and offer CDMO/CMO services in the pharmaceutical industry.


10. Juniper Biologics

Juniper Biologics is a pharmaceutical company specializing in gene therapy and oncology. They offer innovative treatments for rare diseases and provide supportive care for patients. With a focus on accessibility and ESG commitments, their mission is to improve the health and quality of life of patients everywhere.


11. Precision Value & Health

Precision Medicine Group is an integrated team of experts specializing in advanced lab sciences, translational informatics, regulatory affairs, payer insights, and marketing communications. We help pharmaceutical and life-sciences clients navigate the challenges of product development and commercialization in a rapidly evolving environment.


12. Instinctif Partners

  • Website: instinctif.com
  • Headquarters: London, England, United Kingdom
  • Founded: 2007
  • Headcount: 201-500
  • Latest funding type: Acquired
  • LinkedIn

Instinctif Partners is an EMEA business communications consultancy offering a values-based professional advisory service.


13. SmartAnalyst

SmartAnalyst is an investment advisory company that specializes in providing intelligence and insights to the pharmaceutical and biotech industry. They work with leading global pharma companies, offering services in strategy, market research, forecasting, and value assessment.


14. Inova.io

  • Website: inova.io
  • Headquarters: Lyon, Auvergne-Rhône-Alpes, France
  • Founded: 2010
  • Headcount: 51-200
  • Latest funding type: Acquired
  • LinkedIn

Inova is a dedicated biopharma platform that helps companies accelerate their partnering activities throughout the entire partnering lifecycle. It offers an all-in-one solution that is fully scalable, making it suitable for teams of all sizes. Inova enables teams to manage their business development and alliances activities with enhanced data quality, compliance, security, and confidentiality.


15. Beacon Targeted Therapies

Beacon Intelligence provides detailed views and accurate analysis for drug developers in various therapeutic classes. Their solutions include Beacon Gene Therapy, Beacon Cancer Vaccine, Beacon Checkpoint, Beacon Cytokine, Beacon RNA, Beacon Microbiome, Beacon Oncolytic Viruses, Beacon ADC, Beacon TPD, and Beacon Bispecific.


16. PSNResearch

  • Website: psnresearch.com
  • Headquarters: Charlottesville, Virginia, United States
  • Founded: 1997
  • Headcount: 201-500
  • LinkedIn

PSNRESEARCH is a full-service global Contract Research Organization (CRO) with over 500 employees in 15 offices across Northern & Southern America, Europe and Australia. We offer superior clinical development services to biotechnology, pharmaceutical companies and independent institutions acting as sponsors who wish to have a dedicated and cost effective partner. Our focus, since inception in 1997, is to provide a personalized alternative to large CROs by offering the highest professional added value. PSNRESEARCH is large enough to cover any kind of clinical development program, but small enough to give the personal attention and flexibility to each project. Our experts have worked in clinical trials for over 25 years gaining extensive experience in oncology, neurology, cardiovascular diseases, gastroenterology, rheumatology, immunology as well as a host of other therapeutic areas. PSNRESEARCH has developed a competitive cost operational approach based upon a flat management structure with low overheads combined with the highest level of performance and quality standards in clinical development activities. An unrivalled local expertise on regulatory authority strategies, ethics review processes and relations with specialized investigators enable us to provide proven competitive timelines and exceed Sponsor´s expectations.


17. Alacrita Consulting

  • Website: alacrita.com
  • Headquarters: Cambridge, Massachusetts, United Kingdom
  • Founded: 2009
  • Headcount: 51-200
  • LinkedIn

Alacrita is a pharma and biotech consulting firm that provides clients with precisely relevant support on a range of R&D and business issues. With a purpose-built network of over 500 subject-matter experts, Alacrita leverages the first-hand experience of consultants who have spent their careers in discovering, developing, manufacturing, and commercializing drug products.


18. BioPharma Dive: Biotech and Pharma news

BioPharma Dive provides in-depth journalism and insight into the most impactful news and trends shaping biotech and pharma. The newsletter and website cover topics ranging from clinical readouts to FDA approvals, gene therapy to drug pricing and M&A to research partnerships. BioPharma Dive is a leading industry publication operated by Industry Dive. Our business journalists spark ideas and shape agendas for 13+ million decision-makers in the most competitive industries.


19. OncoBay Clinical

  • Website: oncobay.com
  • Headquarters: Tampa, Florida, United States
  • Founded: 2019
  • Headcount: 11-50
  • Latest funding type: Acquired
  • LinkedIn

OncoBay Clinical is a boutique CRO specializing in immuno-oncology clinical development. With a focus on providing custom-curated services to biopharma and biotech companies, OncoBay offers quality results, speed, and unmatched value. The organization is comprised of experienced leaders in clinical oncology who are dedicated to positively impacting the lives of people with cancer.


20. Versant Ventures

Versant Ventures is a global investment firm specializing in the biotechnology sector. They have a team of multi-disciplinary scientists working in state-of-the-art laboratory facilities to launch novel biotechnology companies with academic founders.


21. Pharmaceutical Executive

Pharmexec.com is a platform that provides information, insights, and analysis on the pharmaceutical and biopharmaceutical industry.


22. F-Prime Capital

F-Prime Capital is a global investment firm that creates and invests in healthcare and technology companies. They have a diverse portfolio of over 200 companies across the US, Europe, and Asia, including 29 that were started from scratch. F-Prime Capital aims to improve lives all over the world through their investments and partnerships.


23. EXUMA Biotech

  • Website: exumabio.com
  • Headquarters: West Palm Beach, Florida, United States
  • Founded: 2015
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

EXUMA Biotechnology is a clinical-stage biotechnology company that specializes in the discovery and development of cell and gene therapies for solid & liquid tumors.


24. Gennao Bio

  • Website: gennao.com
  • Headquarters: Hopewell, New Jersey, United States
  • Founded: 2020
  • Headcount: 11-50
  • Latest funding type: Series A
  • LinkedIn

Gennao.com is a biopharmaceutical company specializing in gene monoclonal antibody (GMAB) technology. Their unique technology enables the systemic delivery of multiple types of nucleic acids directly into cells while preserving therapeutic function.


25. Xcell Biosciences

  • Website: xcellbio.com
  • Headquarters: San Francisco, California, United States
  • Founded: 2012
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

Xcell Biosciences is the world's first tumor microenvironment focused cell and drug screening platform. They offer cell and drug therapy potency assays, with a special focus on CAR-T therapy. Their innovative Avatar AI technology allows users to develop rapid and accurate potency assays for cell therapy products in immunosuppressive tumor microenvironments.


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