The industry of ocular drug delivery focuses on the development and provision of innovative treatments and therapies for ophthalmic diseases. Companies within this industry have unique expertise in producing sustainable, long-lasting medication for serious eye conditions. They not only conceive and create efficient therapeutics but also rigorously test them through preclinical research and clinical trials. From formulation expertise to delivery studies, these companies bridge the gap between innovative ideas and fully realized pharmaceutical products. As scientific advancements continue, this industry is progressively moving towards more targeted and localized treatments to better combat eye diseases.


Top 28 Ocular Drug Delivery Companies

1. Ocular Therapeutix, Inc.

  • Website: ocutx.com
  • Headquarters: Bedford, Massachusetts, United States
  • Founded: 2006
  • Headcount: 51-200
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Ocutx.com is a biopharmaceutical company leveraging its formulation expertise to develop transformational drug treatments for ophthalmic diseases.


2. EyePoint Pharmaceuticals

  • Website: eyepointpharma.com
  • Headquarters: Watertown, Massachusetts, United States
  • Founded: 1987
  • Headcount: 51-200
  • Latest funding type: Post Ipo Debt
  • LinkedIn

EyePoint Pharmaceuticals, Inc. is a pharmaceutical company dedicated to developing and commercializing innovative therapeutics to improve the lives of patients with serious eye disorders. With a focus on transforming the treatment of wet AMD, diabetic retinopathy, and retinal vein occlusion, EyePoint offers a range of products including YUTIQ and DEXYCU. With their expertise in sustained-release drug delivery and localized treatments, they aim to provide long-lasting relief for debilitating eye diseases.


3. Iris Pharma

  • Website: iris-pharma.com
  • Headquarters: La Gaude, Provence-Alpes-Cote D&S;Azur, France
  • Founded: 1989
  • Headcount: 51-200
  • Latest funding type: Acquired
  • LinkedIn

Iris Pharma is an ophthalmic Contract Research Organization (CRO) that specializes in preclinical research and clinical trials for ocular innovations. They offer a range of services including efficacy and proof of concept testing, ocular pharmacokinetics, and formulation and delivery studies. With a focus on ophthalmology, Iris Pharma helps clients bridge the gap between innovation and pharmaceutical products in the field of ocular therapies.


4. PYC Therapeutics (ASX: PYC)

  • Website: pyctx.com
  • Headquarters: San Diego, California, United States
  • Founded: 2005
  • Headcount: 51-200
  • LinkedIn

PYC Therapeutics is a company specializing in RNA therapeutics, specifically in the delivery of therapeutic cargo into target cells. With a focus on inherited ocular diseases and neurodegenerative diseases, they are developing peptide conjugated PMOs and Antisense Oligonucleotides called Phosphorodiamidate Morpholino Oligomers (PMOs) for safe and effective delivery. Their revolutionary delivery technology uses a proprietary library of naturally derived Cell Penetrating Peptides (CPPs).


5. Eyenovia, Inc.

  • Website: eyenovia.com
  • Headquarters: New York, New York, United States
  • Founded: 2014
  • Headcount: 51-200
  • Latest funding type: Post Ipo Debt
  • LinkedIn

Eyenovia, Inc. is a ophthalmic technology company that develops the Optejet® delivery system for various therapeutic programs. They offer drug-device combinations for mydriasis, presbyopia, and pediatric progressive myopia. Eyenovia's innovative eye medication delivery technology aims to improve effectiveness, safety, and patient compliance. With the potential for Bluetooth capability, the Optejet® dispenser can track patient adherence. It also reduces systemic exposure and toxicity compared to traditional eyedroppers, resulting in a better tolerability and safety profile for topical treatments.


6. Clearside Biomedical, Inc.

  • Website: clearsidebio.com
  • Headquarters: Alpharetta, Georgia, United States
  • Founded: 2012
  • Headcount: 11-50
  • Latest funding type: Post Ipo Debt
  • LinkedIn

Clearside Biomedical is a company dedicated to redefining the treatment of retinal diseases. They offer innovative delivery approaches that precisely administer drugs to the site of ocular conditions, specifically targeting the back of the eye. Their proprietary technology utilizes the suprachoroidal space to spread drug products towards diseased tissue, providing unprecedented access to the back of the eye.


7. PolyActiva

  • Website: polyactiva.com
  • Headquarters: Melbourne, Vic, Australia
  • Founded: 2010
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

PolyActiva is a company that specializes in the development and production of biodegradable implants for ophthalmic diseases. Their versatile Prezia Sustained Drug Delivery Technology platform allows for precise and controlled drug delivery, improving patient outcomes and quality of life. They are focused on delivering the future of ophthalmic medicine.


8. Neurotech Pharmaceuticals, Inc.

Neurotech Pharmaceuticals is a company focused on providing long-term treatment options for patients with Macular Telangiectasia (MacTel), a bilateral retinal disease that causes a gradual loss of central vision. Their delivery system releases Ciliary Neurotrophic Factor (CNTF), a protein that protects against the loss of photoreceptors. They manufacture implantable devices containing genetically-modified cells for sustained release of therapeutics. Their goal is to help MacTel patients maintain their vision and quality of life.


9. Oxular

  • Website: oxular.com
  • Headquarters: Oxford, England, United Kingdom
  • Founded: 2014
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

Oxular is a limited company registered in England and Wales. They are committed to transforming the treatment paradigm for sight-threatening retinal disorders by providing safe, durable therapeutics that are precisely delivered to specific ocular tissues to control disease activity.


10. Eyevensys

  • Website: eyevensys.com
  • Headquarters: Paris, Ile-De-France, France
  • Founded: 2008
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

Eyevensys is a clinical-stage biotechnology company that specializes in non-viral gene therapies for ophthalmic diseases. They offer revolutionary treatments for eye diseases using their innovative non-viral gene therapy platform.


11. Orbital Itn

  • Website: orbital-itn.eu
  • Headquarters: Waterford, County Waterford, Ireland
  • Founded: 2019
  • Headcount: 11-50
  • LinkedIn

ORBITAL ITN is an EU-funded Marie Sklodowska-Curie Innovation Training Network that aims to train 15 PhD students across Europe to develop drug delivery technologies for treating posterior segment diseases in the eye. Through research and training, ORBITAL strives to improve the quality of life and clinical outcomes for patients with age-related macular degeneration and diabetic retinopathy.


12. JeniVision

  • Website: jenivision.com
  • Headquarters: Irvine, California, United States
  • Headcount: 11-50

JeniVision is an early clinical stage biopharmaceutical company specializing in developing advanced therapies for major ophthalmic diseases using its proprietary non-invasive ocular delivery platform.


13. Aciont Inc

  • Website: aciont.com
  • Headquarters: Salt Lake City, Utah, United States
  • Founded: 2015
  • Headcount: 11-50
  • LinkedIn

Aciont Inc is a biopharmaceutical company in Salt Lake City focusing on developing noninvasive therapeutics for sight-threatening diseases in ophthalmology using its Visulex technology platforms.


14. MediPrint Ophthalmics

  • Website: mediprintlens.com
  • Headquarters: San Diego, California, United States
  • Founded: 2001
  • Headcount: 1-10
  • Latest funding type: Series A
  • LinkedIn

Enhancing vision for life with a patented contact lens based drug delivery portfolio.


15. Re-Vana Therapeutics

  • Website: revanatx.com
  • Headquarters: Belfast, Northern Ireland, United Kingdom
  • Founded: 2015
  • Headcount: 1-10
  • LinkedIn

Re-Vana is developing photocrosslinked technologies for delivery of a wide range of therapeutics that may dramatically extend the time between intravitreal, topical or other injectable routes of administrations to the eye. In addition, we can reduce or potentially eliminate the need for topical drug delivery. Our technologies may lead to a new generation of drugs that will only require 1-2 intravitreal or anterior segment administrations per year. The Re-Vana platforms may also be used with many drugs that have recently become generics or biosimilars that have demonstrated outstanding efficacy for short durations of time.


16. Kedalion Therapeutics

  • Website: kedalionthera.com
  • Headquarters: Menlo Park, California, United States
  • Founded: 2015
  • Headcount: 1-10
  • Latest funding type: Series B
  • LinkedIn

Kedalion Therapeutics is a clinical-stage, venture-funded ophthalmic drug company based in Menlo Park, CA. Kedalion's AcuStream technology delivers topical drugs to the eye in a precise and accurate manner that enables comparable efficacy with an 80% reduction in dose compared to standard drops, and a significantly improved side effect profile along with patient comfort and convenience following self-administration.


17. EyeCRO

  • Website: eyecro.com
  • Headquarters: Oklahoma City, Oklahoma, United States
  • Founded: 2005
  • Headcount: 11-50
  • LinkedIn

EyeCRO is a global leader in preclinical ophthalmic research, specializing in examining the efficacy of novel test agents and therapeutic modalities. They offer a wide range of well-established models and optimized techniques to generate reproducible datasets with meaningful endpoints. With over two decades of experience in vision research, their expert scientists help researchers and developers select the right model and experimental design.


18. Entod Pharmaceuticals

ENTOD Pharma is a pharmaceutical company that specializes in the development and manufacturing of Ophthalmic, ENT and Dermatology products. With over 150 finished products, they offer a wide range of high-quality medicines to patients worldwide.


19. Glint Pharmaceuticals

Glint Pharmaceuticals is a company that develops drug delivery methods such as contact lens. The products are not yet approved by the FDA.


20. Scotia Vision Consultants LLC

Strategic Consulting Company specializing in: 1) Global Ophthalmology (Pharmaceuticals, Medical Devices, Drug Delivery) including Cataract, Retina, Anti Inflammatory, Glaucoma. 2) Start ups or early stage companies. Marketing & Strategic Planning Product Launch Planning International Assignments 3) Multiple clients with innovative and disruptive technologies including start ups with femtosecond laser technology, implantable bionic eye, new retinal drug, unique clinical research model, glaucoma.


21. iVeena

  • Website: iveenamed.com
  • Headquarters: Salt Lake City, Utah, United States
  • Founded: 2006
  • Headcount: 1-10
  • Latest funding type: Series Unknown
  • LinkedIn

iVeena is a clinical stage ophthalmology company developing a non-surgical, non-invasive, pharmacologic innovation. This novel disease modifying intervention addresses a significant unmet need in the advancement of corneal diseases and myopic conditions. The company’s lead programs comprise of novel proprietary products IVMED-80 for keratoconus and IVMED-85 for myopia.


22. DrugDel Consulting LLC

DrugDel Consulting, LLC is a pharmaceutical consultancy that provides a full range of technical and regulatory advisory services for the development of ophthalmic or ocular dose forms and products with particular emphasis on creating effective, stable and safe formulations and controlled release systems. Services include inventive inputs and IP guidance, full life-cycle project planning, management of 3rd party contract services or strategic partners, and technical and regulatory documentation.


23. Intratus, INC.

Intratus is a life sciences company that specializes in the treatment of a multitude of ophthalmic diseases.


24. Center for Nanomedicine

  • Website: cnm-hopkins.org
  • Headquarters: Baltimore, Maryland, United States
  • Headcount: 1-10

Center for Nanomedicine is a company that operates in the Pharmaceuticals industry. It employs 11-20 people and has $0M-$1M of revenue. The company is headquartered in Baltimore, Maryland.


25. Powered Research, LLC

Powered Research is a preclinical CRO specializing in non-GLP ophthalmic models for life science R&D companies. They offer a range of services including custom model development, pharmacology, toxicology, histology & histopathology, pharmacokinetics, drug delivery, and medical devices.


26. TissueGen, Inc.

TissueGen is a company specializing in transformative drug delivery technologies. With a focus on reducing treatment burden and improving clinical outcomes, TissueGen creates life changing treatment modalities for patients and caregivers, targeting both acute and chronic conditions.


27. Everads Therapy Ltd

Everads Therapy is an early-stage life sciences company developing the next generation of retinal treatment delivery technologies. With the goal of overcoming significant challenges in current treatment methodologies for retinal and macular diseases, Everads' delivery system offers the promise of improving the efficacy and safety of existing and potential drug therapies. Established in 2017, Everads Therapy operates within the RAD Biomed incubator in Tel Aviv, Israel. Its underlying technologies have been licensed from the Sheba Medical Center at Tel Hashomer.


28. Lubrizol Life Science

Lubrizolcdmo.com is the website of Lubrizol Life Science Health, a Contract Development and Manufacturing Organization (CDMO) that provides pharmaceutical development and manufacturing services.


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