Biopharmaceutical industry primarily involves the creation and manufacturing of drugs using living systems. Michigan's thriving biopharmaceutical sector includes leading ventures that focus on a wide array of medical fields such as neurological health and cardiovascular systems. These companies develop and launch innovative therapies to address various health conditions, enhancing the quality of patient care and life expectancy. With cutting-edge research facilities, proficient professionals, and a commitment to health improvement, the sector in Michigan shows a promising future, playing a significant role in advancing healthcare globally.


Top 20 biopharmaceutical companies in Michigan

1. Corium, Inc.

  • Website: corium.com
  • Headquarters: Grand Rapids, Michigan, United States
  • Founded: 1999
  • Headcount: 201-500
  • Latest funding type: Private Equity
  • LinkedIn

Corium is a commercial-stage biopharmaceutical company that specializes in the development and commercialization of central nervous system (CNS) healthcare therapies. They provide clinicians with important treatment options for patients, their families, and their caregivers.


2. Rockwell Medical, Inc.

  • Website: rockwellmed.com
  • Headquarters: Wixom, Michigan, United States
  • Founded: 1995
  • Headcount: 201-500
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Rockwell Medical is a commercial healthcare company focused on providing life-sustaining products for patients suffering from blood disorders and diseases associated with the kidney. They are committed to improving patient outcomes with innovative drug therapies.


3. Esperion - The Lipid Management Company

  • Website: esperion.com
  • Headquarters: Ann Arbor, Michigan, United States
  • Founded: 2008
  • Headcount: 201-500
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Esperion Therapeutics is a pharmaceutical company specializing in cardiovascular and cardiometabolic therapies. They aim to develop treatments focused on reducing cholesterol levels. Their pipeline includes innovative options to reduce LDL-cholesterol, with two treatments already approved in the U.S. and Europe. Esperion is committed to addressing the unmet need in cholesterol education and patient advocacy. They are harnessing innovative science to explore new therapies for cardiovascular and cardiometabolic risk.


4. Nerviano Medical Sciences - Part of NMS Group

  • Website: nervianoms.com
  • Headquarters: Nerviano, Michigan, United States
  • Founded: 2004
  • Headcount: 51-200
  • Latest funding type: Private Equity
  • LinkedIn

Nerviano Medical Sciences is an innovative oncology research and development company. As a subsidiary of the NMS Group, we specialize in the discovery and clinical development of small molecule NCEs for personalized cancer treatment. Our expertise lies in novel mechanisms of action and drug targets, with a focus on kinase inhibitors and Antibody-Drug Conjugates (ADCs). We collaborate with academia, clinical investigators, and industrial partners to advance our programs and seek strategic collaborations for global commercialization.


5. Genomenon, Inc

  • Website: genomenon.com
  • Headquarters: Ann Arbor, Michigan, United States
  • Founded: 2014
  • Headcount: 51-200
  • Latest funding type: Series B
  • LinkedIn

Genomenon is a leading provider of genomic search engine technology and solutions for the clinical and pharmaceutical industries. They offer a comprehensive source of genomic evidence, allowing researchers and clinicians to quickly and efficiently search and interpret genetic variants. With their powerful Mastermind platform, they enable drug discovery, clinical trial target selection, and diagnostic decision-making. Genomenon is known for their speed, accuracy, and extensive database of indexed genomic articles and supplemental data sets.


6. Ocuphire Pharma

  • Website: ocuphire.com
  • Headquarters: Farmington Hills, Michigan, United States
  • Founded: 2018
  • Headcount: 11-50
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Ocuphire is a pharmaceutical company specializing in ophthalmic solutions and treatments. They are focused on developing innovative drugs for various eye conditions, such as presbyopia and mydriasis reversal. With a strong management team and partnerships, Ocuphire aims to provide effective solutions for patients in need.


7. Metabolic Solutions Development Company

  • Website: msdrx.com
  • Headquarters: Kalamazoo, Michigan, United States
  • Founded: 2006
  • Headcount: 11-50
  • Latest funding type: Debt Financing
  • LinkedIn

Metabolic Solutions Development Company (MSDC) is a drug discovery and development company specializing in investigating new molecular targets and developing novel therapeutics for metabolic diseases associated with age-related mitochondrial dysfunction, particularly insulin resistance and type 2 diabetes.


8. Lycera

  • Website: lycera.com
  • Headquarters: Ann Arbor, Michigan, United States
  • Founded: 2006
  • Headcount: 11-50
  • Latest funding type: Series B
  • LinkedIn

Lycera is a biotechnology company specializing in immune modulation and developing innovative therapeutics for autoimmune disease and cancer. With a focus on RORgamma agonists, Lycera's integrated research teams are transforming proprietary research findings into novel compounds advancing in clinical and preclinical studies, aiming to bring original solutions to patients with the greatest need.


9. Asalyxa Bio

  • Website: asalyxabio.com
  • Headquarters: Southfield, Michigan, United States
  • Founded: 2020
  • Headcount: 11-50
  • Latest funding type: Seed
  • LinkedIn

Asalyxa Bio is a company that focuses on developing microparticle-based immune cell targeting therapy to treat significant unmet medical needs.


10. Tetra Therapeutics

  • Website: tetratherapeutics.com
  • Headquarters: Grand Rapids, Michigan, United States
  • Founded: 2010
  • Headcount: 11-50
  • Latest funding type: Acquired
  • LinkedIn

Tetra Therapeutics is a science-focused company that specializes in developing innovative drugs aimed at treating cognitive impairment and memory loss caused by traumatic brain injury, dementias, and Fragile X Syndrome.


11. Peptinovo Biopharma

  • Website: peptinovo.com
  • Headquarters: Ann Arbor, Michigan, United States
  • Founded: 2018
  • Headcount: 1-10
  • LinkedIn

Peptinovo is a biotech company developing a novel peptide-based drug delivery platform for cancer treatment that safely delivers stronger doses of proven drugs directly into tumors while reducing exposure to healthy tissue.


12. Pharmadvances

PharmAdvances.com is a technology company specialized in providing a wide range of solutions and services to the pharmaceutical industry.


13. BlueWillow Biologics, Inc.

  • Website: bluewillow.com
  • Headquarters: Ann Arbor, Michigan, United States
  • Founded: 2000
  • Headcount: 11-50
  • Latest funding type: Grant
  • LinkedIn

BlueWillow is a clinical-stage biotech company specializing in intranasal adjuvanted antigen delivery platforms for mucosal vaccines. Their proprietary oil-in-water emulsion adjuvant technology enables the development of intranasal vaccines against respiratory and sexually transmitted diseases. With a focus on safety and a broad range of antigen types, BlueWillow aims to elicit a balanced mucosal, cellular, and systemic immune response for robust and durable protection.


14. Proteos

  • Website: proteos.com
  • Headquarters: Kalamazoo, Michigan, United States
  • Founded: 2003
  • Headcount: 11-50
  • LinkedIn

Proteos.com offers reliable recombinant protein services, with over 15 years of experience. They produce a diverse range of proteins, including antibodies, enzymes, and hormones, with high purity and monodispersity. They also provide real-time communication for data-driven decisions in drug discovery, with flexible experimental designs and continual examination of project trajectory. Proteos.com offers customizable fit-for-purpose products and workflows, working alongside customers to increase the likelihood of a successful discovery program. They also provide protein purification, analysis services, and antibody production capabilities.


15. MPR Development Group

  • Website: mpr-cro.com
  • Headquarters: Farmington Hills, Michigan, United States
  • Founded: 2003
  • Headcount: 11-50

MPR Development Group is a global clinical research organization offering full-service research in therapeutic areas such as oncology, hematology, CNS & psychiatry, and metabolic, cardiology & respiratory.


16. Lead BioPharma Consulting, LLC

Lead BioPharma Consulting (LBC) is a consulting company that specializes in pharmacology, translational medicine/biomarkers, and project management for the pharmaceutical, biotech, and medical device industries.


17. Truetiva

Truetiva specializes in first-stage scientific discovery for the hemp industry, with a focus on technologies that increase the bioavailability of cannabinoids, treat dermatological conditions, and increase the effectiveness of cancer therapeutics.


18. Oxford Biomedical Research, Inc.

Oxford Biomedical Research is a company that provides biomedical researchers with tools for the analysis of Oxidative Stress and Chronic Inflammation. Their products and services help researchers understand important risk factors for various human illnesses such as cancer, cardiovascular disease, diabetes, and neurodegeneration.


19. Integrated Nonclinical Development Solutions, Inc. (INDS)

  • Website: inds-inc.com
  • Headquarters: Ann Arbor, Michigan, United States
  • Founded: 2007
  • Headcount: 11-50
  • LinkedIn

Integrated Nonclinical Development Solutions (INDS) is a drug development consulting company specializing in nonclinical and toxicology support. It provides clients with expertise in traditional and alternative paradigms to advance compounds in all major therapeutic areas to clinical trials. INDS also offers SEND Explorer® software and innovative informatics solutions including state-of-the-art data warehousing, data visualization, interpretations and automated reporting tools.


20. Gemphire Therapeutics

  • Website: gemphire.com
  • Headquarters: Livonia, Michigan, United States
  • Founded: 2011
  • Headcount: 11-50
  • LinkedIn

NeuroBo Pharmaceuticals, Inc. is a clinical-stage biotechnology company focused on developing innovative treatments for chronic liver and related metabolic diseases.


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