The biotechnology industry in Minnesota is a thriving ecosystem that's made up of diverse enterprises. From groundbreaking research tools to drug-testing solutions and advanced medical device manufacturing, these companies strive to lead innovation in life sciences. The sector not only contributes significantly to the state's economic health but is also instrumental in pushing the boundaries of medical and scientific frontiers. The coming years are expected to witness further growth and expansion, backed by increased investments, regulatory support, and a strong scientific community.


Top 22 biotechnology companies in Minnesota

1. Bio-Techne

  • Website: bio-techne.com
  • Headquarters: Minneapolis, Minnesota, United States
  • Founded: 1981
  • Headcount: 1001-5000
  • Latest funding type: Ipo
  • LinkedIn

Bio-Techne is a leading provider of life science research tools, specializing in biotechnology and clinical diagnostics. They offer a wide range of innovative products and services, including cell culture reagents, immunoassay solutions, and genetic analysis tools. Their mission is to empower scientists and healthcare professionals to advance their research and improve patient outcomes.


2. Premier Biotech, Inc.

  • Website: premierbiotech.com
  • Headquarters: Minneapolis, Minnesota, United States
  • Founded: 2009
  • Headcount: 51-200
  • Latest funding type: Acquired
  • LinkedIn

Premier Biotech is a company that specializes in designing, developing, and commercializing products and services in the drugs of abuse testing industry. They offer innovative urine and oral fluid testing solutions for rapid drug screening. Their goal is to provide efficient and accurate testing methods that change the game in the industry.


3. Lifecore Biomedical

  • Website: lifecore.com
  • Headquarters: Chaska, Minnesota, United States
  • Founded: 1965
  • Headcount: 201-500
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Lifecore Biomedical is a fully integrated Contract Development and Manufacturing Organization (CDMO) specializing in specialty formulation, aseptic filling, and final packaging of complex medical devices and injectable pharmaceuticals. With FDA-approved facilities and certifications from global regulators, Lifecore offers reliable and high-quality manufacturing solutions.


4. Pelican BioThermal

Pelican BioThermal is a company that specializes in biopharma cold chain logistics. They offer solutions to manage temperature-controlled logistics for the pharmaceutical industry. Their services help address emerging challenges and pain points in the industry, including increasing quality demands, expanding distribution range, and optimizing total cost of ownership.


5. Vyriad

  • Website: vyriad.com
  • Headquarters: Rochester, Minnesota, United States
  • Founded: 2015
  • Headcount: 51-200
  • Latest funding type: Series B
  • LinkedIn

Vyriad is a company based in Rochester, Minnesota, that specializes in turning viruses into effective anticancer drugs. They have developed proprietary technology to engineer Vesicular Stomatitis Virus (VSV) to boost its anticancer activity and allow noninvasive monitoring in patients. Vyriad works in partnership with Regeneron Pharmaceuticals to evaluate combination therapies and design precision targeted VSV therapies. They offer unique opportunities for employees to discover, innovate, and grow professionally within a dynamic and collaborative environment.


6. Biovest International

Hollow Fiber is a company that offers perfusion hollow fiber bioreactors for cell culture. They provide products, resources, and frequently asked questions about their offerings.


7. Predictive Oncology Inc

Predictive Oncology is a company dedicated to innovating solutions for improving the performance of biologics. They offer AI technology paired with a database of 150K tumor samples to advance cancer therapy and personalized medicine.


8. Recombinetics

  • Website: recombinetics.com
  • Headquarters: Eagan, Minnesota, United States
  • Founded: 2008
  • Headcount: 11-50
  • Latest funding type: Series A
  • LinkedIn

Recombinetics Inc. is a biotechnology company specializing in genetic engineering and xenotransplantation. They are dedicated to addressing the organ shortage crisis by providing a sustainable source of donor organs from genetically engineered pigs. Their solutions include a pipeline of transplantable cells, tissues, and organs for human patient use.


9. StemoniX

  • Website: stemonix.com
  • Headquarters: Maple Grove, Minnesota, United States
  • Founded: 2014
  • Headcount: 11-50
  • Latest funding type: Acquired
  • LinkedIn

StemoniX is a technology company that offers ready-to-use functional microtissues engineered from human pluripotent stem cells. Their microOrgans allow high-throughput human drug screening, saving time and cost. They partner with biopharma, academic, and government institutions to provide functional models, expert services, and advanced analytical algorithms to get medications to patients faster.


10. Syntiron

  • Website: syntiron.com
  • Headquarters: Saint Paul, Minnesota, United States
  • Founded: 2004
  • Headcount: 11-50
  • LinkedIn

Syntiron is a human vaccine research company that offers vaccines against antimicrobial resistant bacteria. It uses the ALLOY Vaccine Platform to target multiple bacterial iron receptors to generate strong, broadly protective vaccines that are easy to make. Their first ALLOY Vaccine targets UTI, which result in more antimicrobial use globally than any other disease.


11. Discovery Genomics

  • Website: discoverygenomics.net
  • Headquarters: Minneapolis, Minnesota, United States
  • Founded: 2000
  • Headcount: 11-50
  • Latest funding type: Acquired

Discovery Genomics offers cutting-edge genomic research services to support healthcare and pharmaceutical industries.


12. BlueAllele

BlueAllele is a gene correction company offering advanced repair template technologies and transformational methods to cure genetic diseases.


13. Microbiologics, Inc.

Microbiologics is a company specializing in microbiology, molecular diagnostic, and virology products and services. They offer a wide range of products and solutions for various laboratory needs.


14. DCI-Biolafitte

DCI-Biolafitte leads the biotechnology equipment industry in the design and production of top-quality bioreactors and fermentors. From benchtop units to industrial-scale systems, DCI-Biolafitte benefits from the design and engineering expertise that comes from decades of being a trusted biotech solutions provider. At DCI-Biolafitte, we take a full-service approach to ensure we exceed your expectations from the initial quote through product installation and ongoing support. The engineers, quality inspectors, and craftspeople at DCI-Biolafitte have decades of experience designing and manufacturing stainless steel bioreactors and fermentors. We seek out the best designers, engineers, and production specialists who have the knowledge, skills, and passion to join our team and maintain our leadership in technology.


15. Humanetics Corporation

  • Website: humaneticscorp.com
  • Headquarters: Minneapolis, Minnesota, United States
  • Founded: 1988
  • Headcount: 11-50
  • Latest funding type: Grant
  • LinkedIn

Humanetics Corporation is a pharmaceutical company that develops and markets radiation modulators to improve cancer patient outcomes and protect civilian and military populations from radiation injuries caused by accidents or terrorism.


16. International Life Science Enterprises

  • Website: il-se.us
  • Headquarters: Saint Paul, Minnesota, United States
  • Headcount: 11-50

International Life Science Enterprises (ILSE) develops and executes global strategies for businesses seeking to enhance their expansion efforts.


17. Kodiak Strategic Consultants

Kodiak Strategic Consulting is a professional consulting firm that specializes in the pharmaceutical and biotechnology industries. They provide services in fundraising and investment, business plan development, drug commercialization, drug development, litigation support services, and regulatory services.


18. Sensus Experience

  • Website: sensusxp.com
  • Headquarters: Minneapolis, Minnesota, United States
  • Founded: 2010
  • Headcount: 11-50
  • LinkedIn

The company provides pharmaceutical products across a range of therapeutic categories.


19. Psyncretis

  • Website: psyncretis.com
  • Headquarters: Minneapolis, Minnesota, United States
  • Headcount: 1-10

Psyncretis, Inc. (sin-CRET-is) is a privately owned company for research and development of pharmaceuticals and biologics for ""nested"" markets -- biochemically-related diseases spanning small (orphan) to large populations. Our mission is to obtain parity in medicinals development between historically underserved and more prevalent diseases, by leveraging and maximizing return on federal support for orphan drug development.


20. Access Genetics

Access Genetics is a company that offers genetic testing services through its subsidiary OralDNA Labs. They provide a wide range of genetic tests and diagnostics to help individuals and healthcare professionals make informed decisions about their health. With their TeleGene™ platform, customers can easily access and manage their genetic test results online.


21. OneOme

  • Website: oneome.com
  • Headquarters: Minneapolis, Minnesota, United States
  • Founded: 2014
  • Headcount: 11-50
  • Latest funding type: Debt Financing
  • LinkedIn

OneOme is a company that provides evidence-based pharmacogenomic solutions to improve patient outcomes and reduce costs through personalized medication decisions.


22. American Preclinical Services, Now Part of NAMSA

American Preclinical Services is a company that provides comprehensive preclinical research services to support the development of medical products. They offer a wide range of services including study design, animal models, regulatory compliance, surgical and imaging capabilities, and data analysis.


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