Biotechnology is an innovation-driven industry that combines biology and technology to develop medications, therapeutics, and various healthcare solutions. In Ohio, many enterprises operate in this sector offering services such as clinical trial management, gene therapy development, and biological therapies manufacture. These companies contribute significantly towards reshaping healthcare and creating new opportunities for treatment. The industry is projected to grow exponentially, thanks to the increasing investment in research and development, cutting-edge technology, and the commercialization of novel therapies to tackle complex diseases.


Top 25 biotechnology companies in Ohio

1. Datatrak International

  • Website: datatrak.com
  • Headquarters: Mayfield Heights, Ohio, United States
  • Founded: 1991
  • Headcount: 51-200
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Datatrak is a provider of eClinical solutions for the pharmaceutical and biotech industries. Their fully configurable platform offers a comprehensive end-to-end solution for clinical trials, including decentralized trials, electronic data capture, imaging and endpoint adjudication, and business intelligence. They aim to streamline trial operations, improve data quality, and reduce costs for their customers.


2. Forge Biologics

  • Website: forgebiologics.com
  • Headquarters: Columbus, Ohio, United States
  • Founded: 2020
  • Headcount: 51-200
  • Latest funding type: Series C
  • LinkedIn

Forge Biologics is a company focused on developing innovative gene therapies to treat patients with devastating rare diseases. They offer end-to-end manufacturing services, from preclinical to commercial, to accelerate gene therapy programs. Their team of diverse and passionate individuals trailblazes a new model for making medicines. They specialize in AAV gene therapies and operate a state-of-the-art GMP facility called 'the Hearth.'


3. AmplifyBio

  • Website: amplify-bio.com
  • Headquarters: West Jefferson, Ohio, United States
  • Founded: 2021
  • Headcount: 201-500
  • Latest funding type: Debt Financing
  • LinkedIn

AmplifyBio is a preclinical contract research organization that specializes in the development and manufacturing of biological therapies. They offer a wide range of services including discovery and characterization, toxicology studies, pathology services, inhalation toxicology, and safety pharmacology. Their goal is to advance the quality of human health and save lives by creating next-generation platforms, tools, and services for the development of accessible therapies and vaccines.


4. DNA Diagnostics Center

  • Website: dnacenter.com
  • Headquarters: Fairfield, Ohio, United States
  • Founded: 1995
  • Headcount: 201-500
  • Latest funding type: Acquired
  • LinkedIn

DNAcenter.com is a leading provider of DNA testing and personalized diagnostics. They offer accurate and trustworthy results for various DNA tests, including paternity, prenatal, immigration, and relationship testing. They also provide lifestyle and ancestry-related tests, such as early gender detection, fertility testing, and ancestry exploration.


5. Andelyn Biosciences

  • Website: andelynbio.com
  • Headquarters: Columbus, Ohio, United States
  • Founded: 2020
  • Headcount: 201-500
  • Latest funding type: Grant
  • LinkedIn

Andelyn Biosciences is a biopharmaceutical manufacturing company that offers a broad range of viral vector and vaccine manufacturing services. They also specialize in manufacturing research and toxicology grade plasmids. With cGMP facilities and rigorous process development guidelines, they provide scalable and reliable solutions for their clients' manufacturing needs.


6. Olon Ricerca Bioscience

Olon Ricerca Bioscience is a company that provides comprehensive on-site analytical chemistry services to support the careers of synthetic chemists. They specialize in chemical technologies, project management, and manufacturing services for drug and chemical development. With significant industrial experience and a strong focus on small molecule development, they are a leading service provider to chemical-based industries.


7. Guild BioSciences

Guild BioSciences is a biotechnology company specializing in the development of innovative morpholinos for therapeutic applications and technologies for sensing microorganisms in food, human fluids, and environmental samples.


8. Affinity Biosciences

Affinity Biosciences is a Life Science and High-Tech company specializing in biochemical products and services for biotechnology, medical research, and pharmaceutical development. Their product line includes antibodies, kits, and peptides. They also offer customization services for phospho and polyclonal antibodies.


9. Navidea Biopharmaceuticals

  • Website: navidea.com
  • Headquarters: Dublin, Ohio, United States
  • Founded: 1983
  • Headcount: 11-50
  • Latest funding type: Post Ipo Debt
  • LinkedIn

Navidea Biopharmaceuticals, Inc. is a precision medicine company that specializes in immuno-targeted products. Their products are designed to identify undetected diseases, improve diagnostic accuracy, enable better clinical decision-making, and provide targeted treatments for cancer, autoimmune conditions, and inflammatory diseases.


10. Flow Pharma Inc

  • Website: flowpharma.com
  • Headquarters: Solon, Ohio, United States
  • Founded: 2002
  • Headcount: 11-50
  • Latest funding type: Series A
  • LinkedIn

Flow Pharma is a biotech company focused on developing revolutionary medicines using immunotherapy. Their unique patented delivery systems are ideal for curative intervention in COVID-19, Ebola, and treatment-resistant cancers.


11. Orange Grove Bio

  • Website: orangegrovebio.com
  • Headquarters: Cincinnati, Ohio, United States
  • Founded: 2019
  • Headcount: 11-50
  • Latest funding type: Series Unknown
  • LinkedIn

Orange Grove Bio is a preclinical drug investment and development firm focused on accelerating drug development for cancer, autoimmune, and inflammatory diseases. They aim to positively transform the quality of life for patients by expediting the development of medical breakthroughs.


12. Ctl-mat

  • Website: ctlmat.com
  • Headquarters: Shaker Heights, Ohio, United States
  • Founded: 2018
  • Headcount: 11-50
  • LinkedIn

CTL-MAT is a company that offers reliable, quantitative, non-animal-based pyrogen testing solutions using the Monocyte Activation Test.


13. Blue Water Vaccines Inc.

  • Website: bluewatervaccines.com
  • Headquarters: Cincinnati, Ohio, United States
  • Founded: 2018
  • Headcount: 11-50
  • Latest funding type: Post Ipo Equity
  • LinkedIn

Blue Water Vaccines is a biopharmaceutical company developing transformational vaccines to address significant health challenges globally. They are headquartered in Cincinnati, OH and hold the rights to proprietary technology developed at the University of Oxford, Cincinnati Children's Hospital Medical Center (CCHMC), and St. Jude Children's Hospital.


14. Celloram Inc.

  • Website: celloram.com
  • Headquarters: Cleveland, Ohio, United States
  • Founded: 2018
  • Headcount: 11-50
  • LinkedIn

Celloram is a biotech company that specializes in small molecule and cell-based therapy development for the treatment of cancer, autoimmune, and metabolic disorders. Their pipeline includes next-generation technologies and innovative research efforts.


15. M1 Labs LLC

M1 Laboratories is a company that offers services in the fields of life sciences, drug discovery and development, and clinical trials.


16. Aerpio Pharmaceuticals

  • Website: aerpio.com
  • Headquarters: Cincinnati, Ohio, United States
  • Founded: 2011
  • Headcount: 11-50
  • Latest funding type: Ipo
  • LinkedIn

Aerpio Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing treatments for ocular diseases and vascular stabilization. Its lead drug candidate, AKB-9778, is currently in Phase 2b clinical development for diabetic retinopathy and other vascular disorders.


17. Progenesis Technologies

  • Website: progenesistech.com
  • Headquarters: South Charleston, Ohio, United States
  • Founded: 2006
  • Headcount: 11-50
  • Latest funding type: Seed
  • LinkedIn

Progenesis Technologies is a biotechnology company that specializes in the engineering and production of tailored alginates and universal vaccines from the bacterium Pseudomonas aeruginosa.


18. Medpace

  • Website: medpace.com
  • Headquarters: Cincinnati, Ohio, United States
  • Founded: 1992
  • Headcount: 1001-5000
  • Latest funding type: Ipo
  • LinkedIn

Medpace is a full-service Contract Research Organization (CRO) that accelerates the advancement of safe and effective medical therapeutics. With a global reach, Medpace offers a wide range of services including clinical trial management, patient recruitment, and drug safety monitoring.


19. InfinixBio

Infinixbio.com offers innovative solutions and services in the biotechnology industry. With cutting-edge technology and experienced professionals, we provide high-quality products and services to clients worldwide.


20. AdaptaLogix

  • Website: adaptalogix.com
  • Headquarters: Dublin, Ohio, United States
  • Founded: 2016
  • Headcount: 51-200
  • Latest funding type: Acquired
  • LinkedIn

AdaptaLogix is a platform that offers comprehensive solutions and features for global financials, approvals, controls, procurement, supply chain, GMP manufacturing, CDMO, and commercial solutions. They streamline GMP manufacturing compliance, providing a system that helps maintain quality and compliance. With a focus on biotech, pharmaceutical, and medical device companies, AdaptaLogix offers solutions tailored to their specific needs.


21. CBG Biotech

CBG Biotech is a company that offers cutting-edge solutions for chemical and biological analyses. They provide a range of products and services including sample preparation, extraction, purification, and analysis equipment. Their expertise in lab testing and research enables them to assist customers in various industries with their specific needs.


22. Triathlon Medical Ventures

  • Website: tmvp.com
  • Headquarters: Cincinnati, Ohio, United States
  • Founded: 2004
  • Headcount: 11-50
  • LinkedIn

Triathlon Medical Ventures is a venture capital firm that invests in early-stage healthcare companies. The company has more than 30 years of industry experience and focuses on pharmaceuticals, surgical devices, and diagnostics.


23. Separopore

  • Website: separopore.com
  • Headquarters: Dublin, Ohio, United States
  • Headcount: 11-50

Separopore is a company specializing in providing bioAffinity matrices and offering a wide range of innovative purification solutions for medical and research purposes.


24. CMC Pharmaceuticals, Inc.

  • Website: cmcpharm.com
  • Headquarters: Solon, Ohio, United States
  • Founded: 2014
  • Headcount: 1-10
  • Latest funding type: Grant
  • LinkedIn

CMC Pharma is an experienced resource for drug product development extending from pre-formulation to commercial scale up with expert team of scientists and laboratory services.


25. CinRx Pharma

  • Website: cinrx.com
  • Headquarters: Cincinnati, Ohio, United States
  • Founded: 2015
  • Headcount: 11-50
  • LinkedIn

CinRx Pharma is an investment firm that specializes in guiding drug candidates through development, focusing on therapies that have the potential to transform treatment and significantly improve patients' quality of life.


Want to find more biotechnology companies?


If you want to find more companies that offer valuable solutions such as eClinical trial systems, gene therapies, and biological therapies development you can do so with Inven. This list was built with Inven and there are hundreds of companies like these globally.


With Inven you'll also get to know the company's:


  • Ownership: Which of these are private equity backed? Which are family-owned?
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...and a lot more!